Normal appendix
CD56 (Dako Omnis)
IVD
CD56 may be present in certain large granular lymphocyte leukemias, small cell lung carcinomas, neural-derived tumors, myelomas, and myeloid leukemias (1–3)
Antibodies to CD56 have been shown to aid in the identification of natural killer (NK) cells, NK-like T cells, neural/neuroendocrine tissues, and in the classification of related neoplasms (4–12)
- Monoclonal Mouse Anti-Human
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Product Details
Features
- Optimized staining performance of both high and low-expression structures
- Crisp and clear staining with no background
- Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis family of instruments
- Consistent, uniform staining with excellent morphology enabled by dynamic gap staining technology on the Dako Omnis family of instruments
- Defined, tested, and approved staining performance for all FLEX RTU antibodies through collaboration with leading international pathology experts
Specifications
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Literature
- Catalogs
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Atlas of Controls
The Atlas of Controls illustrates the staining performance of each antibody in the FLEX Ready-to-Use system.
- Catalogs
- English
- 31 Jul 2026
- 37.96 MB
- Technical Overviews
Support
- Instructions for Use
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Featured References
- Product Description References
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1. Poggi, A. CD Guide: CD56. In Leucocyte Typing VI: White Cell Differentiation Antigens. Proceedings of the 6th International Workshop and Conference, Kobe, Japan, Nov 10–14, 1996; Kishimoto, T.; Kikutani, H.; von dem Borne, A. E. G.; Goyert, S. M.; Mason, D. Y.; Miyasaka, M.; et al., Eds.; Garland Publishing Inc.: New York, London, 1997; pp 1155–1156.
2. Costa, P. NK4: CD56 Workshop Panel Report. In Leucocyte Typing VI: White Cell Differentiation Antigens. Proceedings of the 6th International Workshop and Conference, Kobe, Japan, Nov 10–14, 1996; Kishimoto, T.; Kikutani, H.; von dem Borne, A. E. G.; Goyert, S. M.; Mason, D. Y.; Miyasaka, M.; et al., Eds.; Garland Publishing Inc.: New York, London, 1997; pp 271–272.
3. Leong, A. S.-Y.; Cooper, K.; Leong, F. J. W.-M. Manual of Diagnostic Antibodies for Immunohistology; Oxford University Press: London, 2003; pp 127–129.
4. Levins, K. J.; Prendeville, S.; Conlon, S.; Buggy, D. J. The Effect of Anesthetic Technique on μ-Opioid Receptor Expression and Immune Cell Infiltration in Breast Cancer. J. Anesth. 2018, 32 (6), 792–796. DOI: 10.1007/s00540-018-2554-0.
5. Wojdasiewicz, P.; Poniatowski, Ł. A.; Kotela, A.; Skoda, M.; Pyzlak, M.; Stangret, A.; Kotela, I.; Szukiewicz, D. Comparative Analysis of the Occurrence and Role of CX3CL1 (Fractalkine) and Its Receptor CX3CR1 in Hemophilic Arthropathy and Osteoarthritis. J. Immunol. Res. 2020, 2020, 2932696. DOI: 10.1155/2020/2932696.
6. Dayton, T. L.; Alcala, N.; Moonen, L.; den Hartigh, L.; Geurts, V.; Mangiante, L.; Lap, L.; Dost, A. F. M.; Beumer, J.; Levy, S.; et al. Druggable Growth Dependencies and Tumor Evolution Analysis in Patient-Derived Organoids of Neuroendocrine Neoplasms from Multiple Body Sites. Cancer Cell 2023, 41 (12), 2083–2099.e9. DOI: 10.1016/j.ccell.2023.11.007.
7. Muthusamy, S.; Azhar Shah, S.; Abdullah Suhaimi, S. N.; Kassim, N.; Mahasin, M.; Mohd Saleh, M. F.; Md Isa, N. CD56 Expression in Benign and Malignant Thyroid Lesions. Malays. J. Pathol. 2018, 40 (2), 111–119.
8. Kaur, G.; Nijhawan, R.; Gupta, N.; Singh, N.; Rajwanshi, A. Pleural Fluid Cytology Samples in Cases of Suspected Lung Cancer: An Experience from a Tertiary Care Centre. Diagn. Cytopathol. 2017, 45 (3), 195–201. DOI: 10.1002/dc.23659.
9. Madani, S.; Shahebrahimi, K.; Fazaeli, A.; Khazaei, S.; Kanani, M.; Keshavarz, A. Diagnostic Value of CD56 and Nm23 Markers in Papillary Thyroid Carcinoma. Indian J. Pathol. Microbiol. 2013, 56 (1), 2–5. DOI: 10.4103/0377-4929.116139.
10. Bochen, F.; Balensiefer, B.; Körner, S.; Bittenbring, J. T.; Neumann, F.; Koch, A.; Bumm, K.; Marx, A.; Wemmert, S.; Papaspyrou, G.; et al. Vitamin D Deficiency in Head and Neck Cancer Patients—Prevalence, Prognostic Value and Impact on Immune Function. Oncoimmunology 2018, 7 (9), e1476817. DOI: 10.1080/2162402X.2018.1476817.
11. Gomaa, M. F.; Serag Eldeen, I. F.; Farid, L. A.; El-Saeed, M. M. E.; Abas, A. M.; Aawd, N. M. Uterine Natural Killer Cells Dysregulation in Idiopathic Human Preterm Birth: A Pilot Study. J. Matern. Fetal Neonatal Med. 2017, 30 (15), 1782–1786. DOI: 10.1080/14767058.2016.1224840.
12. Abdel-Aziz, A.; Abdallah, D. Role of Immunohistochemistry in Diagnosis of Papillary Thyroid Carcinoma: The Use of CK19, CD56, P63 and CD117. J. Cancer Tumor Int. 2019, 9 (1), 1–11. DOI: 10.9734/JCTI/2019/v9i130097.
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