Reacts with natural killer cells and a subset of CD4+ and CD8+ T cells in peripheral blood. The antibody is a useful aid for classification of CD56+ T/NK-cell lymphomas. Outside the hematopoietic system, CD56 is expressed in a number of tumors, including neuroblastomas and small cell lung cancer (SCLC).
This product is not available for purchase by the general public.
Product Details
Features
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Specifications
Application
Formalin
HIER
Clone
123C3
Code Number
IR628
Immunogen
Membrane preparation of a small cell lung carcinoma (SCLC) (5). See package insert for reference(s).
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN3.
Solutions
Autostainer Link 48
Species
Mouse Anti-Human
Specificity
In Western blotting of homogenates of SCLC and of an undifferentiated spindle cell sarcoma, the antibody labels a 29 kDa band under reducing conditions. Under non-reducing conditions the 29 kDa band shifted to a 150 kDa band suggesting that the antibody recognizes a protein consisting of at least two subunits (5). See package insert for reference(s).