Acute myeloid leukemia

CD45, Leucocyte Common Antigen (Autostainer Link 48)

Clone 2B11 + PD7/26

CD45 is a transmembrane glycoprotein expressed on most nucleated cells of hematopoetic origin. On human leucocytes, five different isoforms of CD45 have been identified, named ABC, AB, BC, B and 0. Clone 2B11 reacts with all known isotypes of the CD45 family and clone PD7/26 has been clustered as anti-CD45RB. The antibody is a useful aid for classification of lymphoid neoplasms.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

Specifications


Application	Formalin HIER
Clone	2B11 + PD7/26
Code Number	IR751
Immunogen	2B11: Isolated neoplastic cells from a case of T-cell lymphoma/leukemia (1). PD7/26: Human peripheral blood lymphocytes maintained in T-cell growth factor (1). See package insert for reference(s).
Isotype	IgG1, kappa and IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions	Autostainer Link 48
Species	Mouse Anti-Human
Specificity	Anti-CD45 is a mixture of two monoclonal antibodies, clones 2B11 and PD7/26, directed against different epitopes. Clone 2B11 was clustered as anti-CD45 at the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens and reacts with all the known isotypes of the CD45 family (6). Clone PD7/26 was clustered as anti-CD45RB at the Fifth International Workshop and Conference on Human Leucocyte Differentiation Antigens (7). See package insert for reference(s).

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CD45, Leucocyte Common Antigen (Autostainer Link 48)

Product Details

Atlas of Controls

View supported Instructions For Use documents

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