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CD246, ALK Protein (Dako Omnis)

Lung adenocarcinoma

CD246, ALK Protein (Dako Omnis)

Clone OTI1A4

Anaplastic lymphoma kinase (ALK) protein is a receptor tyrosine kinase that is expressed in normal neuronal cells types. Genetic alterations in ALK (fusions, amplifications and mutations) are reported in a variety of tumor types including non-small cell lung carcinoma (NSCLC). The OTI1A4 antibody detects a chimeric ALK protein in subtypes of NSCLC containing an EML4-ALK fusion gene. Results aid in the classification of ALK-positive lung cancer subgroups.

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