CD23 is primarily expressed on B cells and monocytes, including a strong expression on Epstein-Barr Virus-transformed B lymphoblasts. Anti-CD23 is a useful aid for classification of CD23-positive B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (1).
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Product Details
Features
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Specifications
Application
Formalin
HIER
Clone
DAK-CD23
Code Number
IR781
Immunogen
Recombinant protein encoding amino acids 48-248 of human CD23.
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal rabbit antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions
Autostainer Link 48
Species
Mouse Anti-Human
Specificity
In Western blotting the antibody labels a 45 kDa band corresponding to CD23.
1. Rossi S, Laurino L, Furlanetto A, Chinellato S, Orvieto E, Canal F, et al. Rabbit monoclonal antibodies: a comparative study between a novel category of immunoreagents and the corresponding mouse monoclonal antibodies. Am J Clin Pathol 2005,124:295-302.