CD1a Antibody (Concentrate)

Features

Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years’ experience ensuring quality and innovation in antibodies and reagents

Specifications


Application	Frozen Formalin HIER
Clone	010
Code Number	M3571
Immunogen	Human thymus cells.
Isotype	IgG1, kappa
Reagent Provided	Monoclonal mouse antibody provided in liquid form as a tissue culture supernatant (containing fetal bovine serum) dialyzed against 0.05 mol/L Tris-HCl, pH 7.2, and 0.015 mol/L sodium azide.
Solutions	Concentrate
Species	Mouse Anti-Human
Specificity	Monoclonal Anti-Human CD1a, clone 010 (anti-CD1a, clone 010) was classified as CD1a at the Fourth International Workshop and Conference on Human Leucocyte Differentiation Antigens (2). Clone 010 has been shown to immunoprecipitate labeled CD1a from thymus cell lysate and from Langerhans' cell-enriched epidermal cell lysate (2). In the latter, the antibody strongly precipitated the native CD1a molecule (49 kDa molecular weight) and Beta-2-microglobulin (12 kDa molecular weight) but not the trypsin-cleaved CD1a molecule (27 kDa molecular weight) (2). In immunohistochemistry, the antibody has been demonstrated to react with the CD1a cell surface glycoprotein expressed on cortical thymocytes, Langerhans' cells, and interdigitating dendritic (reticulum) cells in frozen and formalin-fixed, paraffin-embedded (FFPE) tissues (1,2). See package insert for reference(s).

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Literature

Technical Overviews

Immunohistochemical Staining Methods - Education Guide, Sixth Edition

The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.

Technical Overviews
English
30 Nov 2021
27.05 MB
PDF

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CD1a (Concentrate)

Product Details

Immunohistochemical Staining Methods - Education Guide, Sixth Edition

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