Reacts with a carbohydrate antigen, termed Lewis X (Lex), X hapten or CD15 antigen, expressed on Reed-Sternberg cells and various other cell types including myeloid cells and epithelial cells. Results aid in the classification of acute myeloid leukemia and chronic myelogenous leukemia, as well as carcinomas derived from various organs (1). The antibody is of value in the identification of Reed-Sternberg cells for classification of Hodgkin's lymphoma.
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Product Details
Features
Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.
Specifications
Application
Formalin
HIER
Clone
Carb-3
Code Number
GA062
Immunogen
Affinity-isolated X-hapten oligopeptide fragment from myelomonocytic leukemia cells.
Isotype
IgM
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN3.
Solutions
Dako Omnis
Species
Mouse Anti-Human
Specificity
In Western blotting of HL60 cell lysates the antibody labels a major band of ~220 kDa corresponding to the expected molecular weight of CD15 (7). See package insert for reference(s).