CD10 is a cell surface metallopeptidase, expressed on early lymphoid progenitor cells and on a small subset of immature B cells in bone marrow, but is lost as the cells reach maturation. CD10 is, however, re-expressed on proliferating B cells and mature neutrophils. The DAK-CD10 antibody may be a useful aid for classification of Burkitt lymphoma, follicular lymphoma, diffuse large B-cell lymphoma and renal cell carcinoma clear cell type.
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