Calponin Antibody (Concentrate)

Features

Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
More than 50 years’ experience ensuring quality and innovation in antibodies and reagents

Specifications


Application	Frozen Formalin Enzyme + HIER
Clone	CALP
Code Number	M3556
Immunogen	Crude human uterus extract (1). See package insert for reference(s).
Isotype	IgG1, kappa
Reagent Provided	Anti-human calponin, CALP is a mouse monoclonal antibody supplied in liquid form as tissue culture supernatant (containing fetal bovine serum) dialyzed against 0.05 mol/L Tris-HCl, pH 7.2 and 0.015 mol/L sodium azide.
Solutions	Concentrate
Species	Mouse Anti-Human
Specificity	Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34 kD form and a 29 kD form (5). Expression of the 29 kD form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle (2-5). In Western blotting, monoclonal anti-calponin, CALP, has been demonstrated to react with only the 34 kD form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin (1). See package insert for reference(s).

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Literature

Technical Overviews

Immunohistochemical Staining Methods - Education Guide, Sixth Edition

The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.

Technical Overviews
English
30 Nov 2021
27.05 MB
PDF

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Calponin (Concentrate)

Product Details

Immunohistochemical Staining Methods - Education Guide, Sixth Edition

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