Caldesmon Antibody (Dako Omnis)

Features

Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.

Specifications


Application	Formalin HIER
Clone	h-CD
Code Number	GA054
Immunogen	Crude human uterus extract (1). See package insert for reference(s).
Isotype	IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN₃.
Solutions	Dako Omnis
Species	Mouse Anti-Human
Specificity	Two closely related variants of human caldesmon have been identified which differ in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non-muscle tissue and cells. Neither of the two variants have been detected in skeletal muscle (3). Monoclonal anti-caldesmon, h-CD, recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin (1). See package insert for reference(s).

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The Atlas of Controls illustrates the staining performance of each antibody in the FLEX Ready-to-Use system.

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Caldesmon (Dako Omnis)