Calcitonin is a 32 amino acid peptide hormone, produced in the parafollicular C cells of the thyroid. Calcitonin acts through its receptors, causing osteoclast-mediated bone resorption and calcium excretion by the kidney. The antibody is useful for the identification of calcitonin-producing C cells and is a useful aid for classification of medullary thyroid carcinoma.
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Product Details
Features
Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.
Specifications
Application
Formalin
HIER
Clone
Polyclonal
Code Number
GA515
Immunogen
Synthetic human calcitonin, aa 1-32, coupled to bovine serum albumin (BSA).
Reagent Provided
Ready-to-use polyclonal rabbit antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN3.
Solutions
Dako Omnis
Species
Rabbit Anti-Human
Specificity
The antibody reacts with human calcitonin. Traces of contaminating antibodies have been removed by solid-phase absorption with human plasma and bovine serum proteins. The antibody labels human thyroid C-cells, and other calcitonin-containing cells strongly and specifically. No non-specific staining has been observed.