C5b-9 Antibody (Concentrate)

Features

Excellent specificity
High lot to lot consistency
Certified manufacturing facilities guarantee full quality control
More than 50 years’ experience ensuring quality and innovation in antibodies and reagents

Specifications


Application	Frozen
Clone	aE11
Code Number	M0777
Immunogen	Purified human MAC (1). See package insert for reference(s).
Isotype	IgG2a, kappa
Reagent Provided	Monoclonal mouse antibody provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, pH 7.2, and containing 15 mmol/L NaN₃.
Solutions	Concentrate
Species	Mouse Anti-Human
Specificity	The clone was initially selected in an ELISA demonstrating reactivity towards the immunizing agent and activated serum (1). In Western blotting of purified components of the TCC the antibody labels the poly-C9 and to a lesser degree the C9 but do not recognize the C5, C6, C7 or the C8 components (1). The antibody reacts with a neoepitope on poly C9 complement factor. This neoepitope is exposed in the solid-phase and membrane form and in the fluid-phase form of the terminal complement complex, but not in native C9. The antibody reacts with both membrane-bound and adsorbed terminal complement complex (5). See package insert for reference(s).

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Literature

Technical Overviews

Immunohistochemical Staining Methods - Education Guide, Sixth Edition

The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.

Technical Overviews
English
30 Nov 2021
27.05 MB
PDF

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C5b-9 (Concentrate)

Product Details

Immunohistochemical Staining Methods - Education Guide, Sixth Edition

View supported Instructions For Use documents

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