Alpha-1-antitrypsin (A1AT) is a 51 kDa glycoprotein mainly synthesized in the liver. It is an acute phase protein and functions as a major inhibitor of serine proteases. A1AT is present in normal liver cells, histiocytes and monocytes, and in a large variety of tumors of both epithelial and mesenchymal differentiation.
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Product Details
Features
Optimized staining performance of both high and low-expression structures
Dako Omnis and the dynamic gap staining technology provides a consistent, uniform staining with excellent morphology
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Dako Omnis
The staining performance of all FLEX RTU antibodies has been defined, tested and approved through collaboration with leading, international pathology experts.
Specifications
Application
Formalin
HIER
Clone
Polyclonal
Code Number
GA505
Immunogen
Alpha-1-antitrypsin isolated from human plasma.
Reagent Provided
Ready-to-use polyclonal rabbit antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L NaN3.
Solutions
Dako Omnis
Species
Rabbit Anti-Human
Specificity
The antibody reacts with human alpha-1-antitrypsin. Traces of contaminating antibodies have been removed by solid-phase absorption with human plasma proteins.
Crossed immunoelectrophoresis: Only the alpha-1-antitrypsin precipitation arch appears when using 12.5 µL the concentrate antibody per cm2 gel area against 2 µL human plasma. Staining: Coomassie Brilliant Blue.