Labels myocardial, skeletal and smooth muscle cells as well as myoepithelial cells. It also reacts with 'myofibroblasts' in the stroma of certain tumors. The antibody is a useful aid for classification of rhabdomyosarcomas, leiomyomas and leiomyosarcomas, and many carcinomas.
This product is not available for purchase by the general public.
Product Details
Features
Excellent specificity
High lot to lot consistency
Optimized for immunohistochemistry (IHC) with validated protocols
Certified manufacturing facilities guarantee full quality control
Dako products are the result of almost 50 years experience ensuring quality and innovation in antibodies and reagents.
Specifications
Application
Formalin
HIER
Clone
HHF35
Code Number
M0635
Immunogen
SDS extracted protein fraction of human myocardium.
Isotype
IgG1, kappa
Reagent Provided
Monoclonal mouse antibody provided in liquid form as tissue culture supernatant in 0.05 mol/L Tris-HCl, pH 7.2 and 0.015 mol/L sodium azide. This product contains stabilizing protein.
Solutions
Concentrate
Species
Mouse Anti-Human
Specificity
Actin does not react with the α-actin of non-muscle (endothelial cells) sources (1). Gel electrophoresis and immunoblots show the specificity of HHF35 to be for the α- and γ-actin isotypes of skeletal, cardiac and smooth muscle (1). See package insert for reference(s).
The focus of the sixth edition of the IHC Guidebook is to provide a comprehensive immunohistochemistry (IHC) resource for lab managers, lab technicians, learning pathologists, and students from around the world.