Labels myocardial, skeletal and smooth muscle cells as well as myoepithelial cells. It also reacts with 'myofibroblasts' in the stroma of certain tumors. The antibody is a useful aid for classification of rhabdomyosarcomas, leiomyomas and leiomyosarcomas, and many carcinomas.
This product is not available for purchase by the general public.
Product Details
Features
Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.
Specifications
Application
Formalin
HIER
Clone
HHF35
Code Number
IR700
Immunogen
SDS extracted protein fraction of human myocardium from a case of idiopathic hypertrophic subaortic stenosis.
Isotype
IgG1, kappa
Reagent Provided
Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions
Autostainer Link 48
Species
Mouse Anti-Human
Specificity
In Western blotting of purified rabbit skeletal muscle actin, extracts of monkey aorta, uterus, diaphragm and heart, the antibody labels 42 kDa protein corresponding to muscle actin of α and γ-actin isotypes, but fails to react with the α-actin of non-muscle (endothelial cells) sources (4). See package insert for reference(s).