Leiomyosarcoma

Actin (Muscle) (Autostainer Link 48)

Clone HHF35

Labels myocardial, skeletal and smooth muscle cells as well as myoepithelial cells. It also reacts with 'myofibroblasts' in the stroma of certain tumors. The antibody is a useful aid for classification of rhabdomyosarcomas, leiomyomas and leiomyosarcomas, and many carcinomas.

Monoclonal Mouse Anti-Human

Features

Optimized staining performance of both high and low-expression structures
Crisp and clear staining with no background
Optimal laboratory efficiency with ready-to-use antibodies on Autostainer Link 48
The staining performance of all antibodies has been defined, tested and approved through collaboration with leading international pathologists. Check the Atlas of Stains - a guide to diagnostic accuracy.

Specifications


Application	Formalin HIER
Clone	HHF35
Code Number	IR700
Immunogen	SDS extracted protein fraction of human myocardium from a case of idiopathic hypertrophic subaortic stenosis.
Isotype	IgG1, kappa
Reagent Provided	Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide.
Solutions	Autostainer Link 48
Species	Mouse Anti-Human
Specificity	In Western blotting of purified rabbit skeletal muscle actin, extracts of monkey aorta, uterus, diaphragm and heart, the antibody labels 42 kDa protein corresponding to muscle actin of α and γ-actin isotypes, but fails to react with the α-actin of non-muscle (endothelial cells) sources (4). See package insert for reference(s).

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