Dissolution Cannula Filters
Cannula filters are a type of dissolution filters that fit on the end of dissolution cannulas and provide filtration when sampling occurs. Agilent Full Flow Filters, where the whole construction of the dissolution cannula filter is made from filter material, offer an increased surface area for filtration. The large surface area greatly increases the filtration capacity and prevents clogging.
Agilent Full Flow Filters are made of either ultrahigh molecular weight polyethylene (UHMWPE) or the polyvinylidene fluoride (PVDF). These dissolution cannula filters are relatively inert and can be used for different sample matrices. PVDF cannula filters are available in those instances where chemical compatibility or sample adsorption is an issue with UHMWPE. These are made of a low protein-binding material that can filter a wide variety of active drug substances. Both UHMWPE and PVDF cannula filters can be used with dissolution cannulas and are available in packs of 100 or 1000.