5400 Fragment Analyzer System for ultra-high-throughput DNA and RNA quality control
5400 Fragment Analyzer System
The 5400 Fragment Analyzer system is compatible with all the same high-quality reagent kits available for the 5300 Fragment Analyzer system. Use quantitative kits for analyzing NGS libraries, large fragment smears, genomic DNA, total RNA, small RNA, and mRNA vaccine. Also, you can use qualitative kits for analyzing PCR amplicons, SSRs/microsatellites, CRISPR-generated mutations, or digested DNA.
- Fragment Analyzer Systems
Product Details
- Robotic integration – Seamlessly integrate with most laboratory automation systems via custom API and powered drawers
- Ultra-high-throughput separations – Get unattended analysis of more than 2,400 samples every 24 hours
- Low cost-per-sample – Choose qualitative or quantitative gel kits that best suit your analysis needs, and realize lower operational costs compared to other analytical instruments
- Easy adoption to changes in your workflow – Choose a shorter or longer array to maximize your runs regarding speed or resolution of individual samples
- Decreased preparation time – Reduce the time needed for instrument setup with no daily array handling requirements and room-temperature-stable reagents
- Broad assay portfolio – Analyze samples ranging from gDNA, NGS libraries, and DNA fragments to total RNA, small RNA, and mRNA vaccines all on one platform
- High-resolution separation – Resolve a wide range of DNA and RNA fragments, and achieve as low as 3 bp resolution with high-sizing accuracy for fragments under 300 bp
- Seamless switching between applications – Load two different gels into the instrument to use different kits within one system setup
- User-friendly software – Automate data scoring, calculate fragment size and concentration, and create, save, and load customized reports and scoring parameters for flagging and smear analysis
- Comprehensive compliance services – Qualify instruments by IQ/OQ services for use in GMP environments
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- Key Literature
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Suitability Testing for IVT mRNA Analysis Using Agilent Fragment Analyzer Systems
This application note provides an example of a suitability study using the Agilent Fragment Analyzer system.
- Application Notes
- English
- 01 Aug 2025
- 750.77 KB
Quality Control in the PacBio HiFi Whole Genome Sequencing Library
Accurate and reliable next-generation sequencing (NGS) results rely on starting with high-quality samples.
- Application Notes
- English
- 02 Jul 2025
- 1.77 MB
CQA Assessment of LNP-Encapsulated IVT mRNA Using Agilent Fragment Analyzer Systems
This technical overview provides examples of CQAs for IVT mRNA, such as size, concentration, purity, and integrity, that can be addressed by the Agilent Fragment Analyzer system.
- Technical Overviews
- English
- 06 Mar 2025
- 381.88 KB
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Sophie Wehren
QC Development Project Lead, Kaneka Eurogentec
“Sometimes we have a sample at midnight, and we have to get a result to the production team before the morning. It’s very easy with the Fragment Analyzer because we have a quick result and an accurate analysis,”
View MoreYanina Panzera
Ph.D., Professor at the University of the Republic (UdelaR) in Montevideo, Uruguay
“We frequently use the Fragment Analyzer system, a parallel capillary electrophoresis system, to perform library size analysis and check library quality.”
View More