5400 Fragment Analyzer System for high-throughput DNA and RNA quality control
5400 Fragment Analyzer System
The 5400 Fragment Analyzer system redefines the bounds of nucleic acid quality control (QC) analysis using automated parallel capillary electrophoresis. Capable of connecting with world-leading robotic systems, analysis of DNA and RNA samples can now be performed around the clock through robotic integration.
The 5400 Fragment Analyzer system is compatible with all the same high-quality reagent kits available for the 5300 Fragment Analyzer system. Use quantitative kits for analyzing NGS libraries, large fragment smears, genomic DNA, total RNA, small RNA, and mRNA vaccine. Also, you can use qualitative kits for analyzing PCR amplicons, SSRs/microsatellites, CRISPR-generated mutations, or digested DNA.
The 5400 Fragment Analyzer system is compatible with all the same high-quality reagent kits available for the 5300 Fragment Analyzer system. Use quantitative kits for analyzing NGS libraries, large fragment smears, genomic DNA, total RNA, small RNA, and mRNA vaccine. Also, you can use qualitative kits for analyzing PCR amplicons, SSRs/microsatellites, CRISPR-generated mutations, or digested DNA.
- Fragment Analyzer Systems
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Product Details
Features
- Robotic integration – Seamlessly integrate with most laboratory automation systems via custom API and powered drawers
- High-throughput separations – Get unattended analysis of more than 2,400 samples every 24 hours
- Low cost-per-sample – Choose qualitative or quantitative gel kits that best suit your analysis needs, and realize lower operational costs compared to other analytical instruments
- Easy adoption to changes in your workflow – Choose a shorter or longer array to maximize your runs regarding speed or resolution of individual samples
- Decreased preparation time – Reduce the time needed for instrument setup with no daily array handling requirements and room-temperature-stable reagents
- Broad assay portfolio – Analyze samples ranging from gDNA, NGS libraries, and DNA fragments to total RNA, small RNA, and mRNA vaccines all on one platform
- High-resolution separation – Resolve a wide range of DNA and RNA fragments, and achieve as low as 3 bp resolution with high-sizing accuracy for fragments under 300 bp
- Seamless switching between applications – Load two different gels into the instrument to use different kits within one system setup
- User-friendly software – Automate data scoring, calculate fragment size and concentration, and create, save, and load customized reports and scoring parameters for flagging and smear analysis
- Comprehensive compliance services – Qualify instruments by IQ/OQ services for use in GMP environments
Specifications
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How It Works
Applications
Literature
- Key Literature
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Best Practices for Analysis of IVT mRNA using the Agilent Fragment Analyzer systems
In this technical overview, best practices for analysis of IVT mRNA are discussed, with particular attention to the use of the Agilent RNA kit and Fragment Analyzer systems.
- Technical Overviews
- English
- 07 Sep 2023
- 1.14 MB
Best Practices for Analysis of In Vitro Transcribed (IVT) mRNA Using the Agilent Fragment Analyzer systems
This technical overview discusses best handling practices for IVT mRNA and analysis with the Fragment Analyzer systems, including sample handling and quantification tips.
- Technical Overviews
- English
- 26 Jun 2023
- 946.95 KB
Comparison of Constant- and Pulsed-Field Electrophoresis Technologies for Analysis of High Molecular Weight and Large DNA Fragments
This application note demonstrates the use of the Agilent Fragment Analyzer and Femto Pulse systems for analysis of high-molecular-weight and large DNA fragments.
- Application Notes
- English
- 22 Jun 2023
- 540.88 KB
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