Agilent ExD Cell 和 Agilent 6545XT AdvanceBio LC/Q-TOF
用于 LC/Q-TOF 的 ExD Cell
ExD Cell 的高 ECD 效率使其能够分析电荷较低 (≥ 2+) 的分析物，克服了电子解离技术长期以来的限制。结合 6545XT 的优势，如超高真空和高达 4000 m/z 的四极杆分离，使其成为自上而下以及自中而下表征大分子蛋白质的理想选择。
- Quadrupole Time of Flight LC/MS
Product Details
- 超高效的 ECD 意味着可以花费更少的时间进行微调以大幅提高性能，而且更适用于难分析和低丰度的多肽和蛋白质。
- 使用 Agilent BioConfirm 12.1 进行自下而上的肽谱分析或使用 ExDViewer 进行自上而下的分析，可以快速、直观和可靠地解读信息丰富的 ECD 谱图。
- 将 ExD Cell 安装在碰撞池后，通过将调谐与上游光学元件分离，简化了操作，从而简化了方法设置。
- ExD Cell 可现场安装，也支持后期安装，帮助您尽可能充分利用对 6545XT LC/Q-TOF 的现有投资。
- 新的化学调谐标准品由添加到调谐混标中的有机可溶性肽（蜂毒素）组成，为常规校准、仪器调谐和 ECD 方法初始化提供了单瓶装溶液。
- 结合 6545XT 的固有优势，如超高真空和高达 4000 m/z 的四极杆分离，使该系统非常适合大分子蛋白质的自上而下和自中而下表征。
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- Application Notes
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Differentiation of Isomeric Amino Acids by Electron Capture Dissociation
Agilent 6545XT AdvanceBio LC/Q-TOF equipped with an ExD cell was used to differentiate isomeric amino acids in a tryptic peptide.
- Application Notes
- English
- 21 May 2026
- 835.33 KB
Top-Down Sequence Analysis of Intact Proteins Using an Agilent AdvanceBio 6545XT LC/Q-TOF with ExD
This application note describes a method for top-down fragmentation using the Agilent 6545XT AdvanceBio LC/Q-TOF with an electron capture dissociation (ExD) cell.
- Application Notes
- English
- 07 Jan 2026
- 790.03 KB
Comprehensive Characterization of Multiple GLP-1 Analogs Using an LC/Q-TOF with Electron Capture Dissociation and Agilent ExDViewer Software
This application note demonstrates the comprehensive sequence analysis and localization of modifications in three synthetic GLP-1 analogs.
- Application Notes
- English
- 14 Apr 2025
- 1.90 MB
Identification of Amino Acid Isomers Using ECD and Agilent 6545XT AdvanceBio LC/Q-TOF
This note shows identification of isobaric residues in peptides and intact proteins with 6545XT AdvanceBio LC/Q-TOF and ExD cell electron capture dissociation.
- Application Notes
- English
- 15 Aug 2024
- 1.21 MB
- Brochures
- Posters
- Site Preparation Checklists
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ExD Cell Site Preparation Checklist
This document is an information guide and checklist prepared for you that outlines the supplies, space, and utility requirements for the system set up in your lab.
- Site Preparation Checklists
- English
- 21 Aug 2024
- 248.36 KB
- User Manuals