xCELLigence RTCA DP - 细胞侵袭和迁移
DP 仪器的三个板位/卡位可满足三个独立的 16 孔电子板,可以平行或彼此独立地进行控制和监测。这种灵活的孔板批量处理模式可实现多用户处理,大大提高了分析效率。该仪器在标准 CO2 细胞培养箱中运行,工作站位于培养箱外部。
使用 RTCA Software Pro 可轻松进行在线数据采集和离线数据分析,符合 FDA 21 CFR Part 11 法规要求。
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Product Details
- xCELLigence RTCA DP 型号最多可运行三个独立的电子 16 孔板(E-Plate 16 或 CIM-Plate 16)
- CIM-Plate 16 中的每个孔均为电子集成的 Boyden 小室,可以实时(以秒或分钟为间隔)监测细胞侵袭和迁移,无需外源标记
- 使用 E-plate 16 的非侵入性和无标记实时阻抗分析能以高灵敏度、准确度和重现性测量细胞健康、活力或对处理的反应
- 以高时间分辨率(从数秒到数天)获取连续数据
- 简单的工作流程便于用户将细胞添加到 E-plates 并在生理条件下开始动力学测量,尽可能缩短手动操作时间
- 直观的 RTCA Software Pro 可分析实时数据,生成各种绘图类型并自动计算细胞杀伤百分比、IC50 或 KT50 等参数
- RTCA Software Pro 符合 FDA 21 CFR Part 11 法规要求,确保电子数据可靠性
细胞阻抗技术说明
细胞阻抗分析的功能单元是一组嵌入微孔板底面的微金电极。当浸入导电溶液(如缓冲液或标准组织培养基)中时,在这些电极间施加电压会使电子离开负极、流经细胞或培养基,然后回到正极形成完整电回路。
Learn More- Application Notes
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xCELLigence Portfolio Cancer Immunotherapy Handbook
Recently updated Cancer Immunotherapy Handbook featuring the latest high impact xCELLigence publications and newly released supporting information.
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- 10 Mar 2023
- 10.21 MB
A New Way to Monitor Virus-Mediated Cytopathogenicity
This application note describes the experimental setup for assessing vesicular stomatitis virus-mediated cytotoxicity of Vero E6 cells and HEK 293 cells using an xCELLigence instrument.
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- 12 Feb 2021
- 358.59 KB
Label-Free Assay for NK Cell‑Mediated Cytolysis
In this application note, a series of experiments demonstrate how the xCELLigence RTCA system can be applied to quantitatively monitor NK cell‑mediated cytolysis without labeling the target cells.
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- 12 Feb 2021
- 699.12 KB
Dynamic Monitoring of Receptor Tyrosine Kinase Activation in Living Cells
This application note highlights the development and utility of an alternative receptor tyrosine kinase assay that uses the impedance‑based xCELLigence system.
- Application Notes
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- 12 Feb 2021
- 1.58 MB
Dynamic Monitoring of G-Protein‑Coupled Receptor Activation in Living Cells
In this application note, a series of experiments demonstrates how the xCELLigence system may be used to monitor functional activation of GPCRs in living cells.
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- 12 Feb 2021
- 1.07 MB
Dynamic Monitoring of Cell Adhesion and Spreading
In this application note, a series of experiments is described to demonstrate that the xCELLigence system is suitable for monitoring cell adhesion and spreading.
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- 12 Feb 2021
- 1007.33 KB
Real-Time and Dynamic Monitoring of Cell Proliferation and Viability for Adherent Cells
This application note shows experiments that were conducted using xCELLigence instruments to assess cell proliferation and drug interaction with different cell lines.
- Application Notes
- English
- 19 Aug 2020
- 1.00 MB
Vaccine and Virology Applications
A collection of studies showing the benefits of xCELLigence RTCA assays over traditional assays. Antiviral drugs, virucides, neutralizing antibodies and other applications are examined.
- Application Notes
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- 02 Jul 2020
- 4.37 MB
Infectious Disease Applications
A compilation of studies demonstrating the application of xCELLigence RTCA to the analysis of bacterial toxins, biofilms, virus titer determination, and other areas of disease.
- Application Notes
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- 02 Jul 2020
- 4.93 MB
Studying Bacterial Biofilms Using Cellular Impedance
Describes the use of Agilent xCELLigence real-time cell analysis (RTCA) instruments for impedance monitoring.
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- 02 Jul 2020
- 1.94 MB
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Dell Ownership Transfer Process
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- 24 Aug 2020
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