Peptide Mapping Resources
In-Depth Resources:
Peptide Mapping and PTM Analysis
The following resources will help you reliably characterize primary sequence and detect PTMs.
Application notes
- In-depth Peptide Mapping with Iterative MS/MS Acquisition on the Agilent 6545XT AdvanceBio LC/Q‑TOF
- Quantitation of Chemical-Induced Deamidation and Oxidation on Monoclonal Antibodies
- An Integrated Workflow for Peptide Mapping of Monoclonal Antibodies
- Making Peptide Mapping Routine with the Agilent 6545XT AdvanceBio LC/Q-TOF
- High Resolution and Rapid Peptide Mapping of Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC and an Agilent 6550 iFunnel Q-TOF LC/MS System
- Workflow Automation for LC/MS: In-Solution Protein Digestion, Peptide Cleanup, and Strong Cation-Exchange Fractionation of Peptides Enabled by AssayMAP Technology
- Rapid Antibody Digestion Enabled by Automated Reversed-Phase Desalting on the Agilent AssayMAP Bravo Platform
- CE/MS and LC/MS Synergy: Complementary Solutions for Peptide Mapping
- Enhancing the Quality of Peptide Mapping Separation for the Analysis of PTM
- LC/MS Analysis of Peptide Mapping with Formic Acid as an Ion‑Pairing Agent
- Peptide Mapping of Glycoprotein Erythropoietin by HILIC LC/MS and RP-LC/MS
- Mapping the Drug Conjugation Sites of an Antibody Drug Conjugate Using Automated Sample Preparation and LC/MS Analysis
- Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System
- Peptide Mapping: A Quality by Design (QbD) Approach
- High-Resolution Mapping of Drug Conjugated Peptides in an ADC Digest: Peptide Map Comparison of mAb and Drug Conjugated mAb
- Fast and Efficient Peptide Mapping of a Monoclonal Antibody (mAb): UHPLC Performance with Superficially Porous Particles
Brochures
- Agilent 6545XT AdvanceBio LC/Q-TOF System: Designed for Biopharma
- Agilent 1290 Infinity II LC—Set New Benchmarks in Efficiency
- Agilent InfinityLab LC Series—Efficient LC Solutions for Any Application and Budget
- Agilent AssayMAP Bravo Platform: Automated Protein and Peptide Sample Preparation for Mass Spec Analysis
- Drug Development and Quality Control: Biopharma Workflow Solutions
- Prepping Biosimilars for a Big Play
Data sheet
Guides and primers
- Keys for Enabling Optimum Peptide Characterizations: A Peptide Mapping “How to” Guide
- Recombinant Protein Characterization—A Primer
- Agilent BioHPLC Column Selection Guide—Your Reference Guide to the Analysis of Biopharmaceuticals and Biomolecules
Videos
- Biopharma Samples-to-Answers Video
- Designed for Biopharma: The 6545XT AdvanceBio LC/Q-TOF System
- AssayMAP Bravo Protein Sample Preparation Platform
On-demand webinars
Go from Samples to Answers. Visit Agilent’s Pharma Biologics and Small Molecules Solutions Pages
For Research Use Only. Not for use in diagnostic procedures.