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Using MassHunter software with your Agilent LC/TQ delivers precise PFAS analysis with powerful data collection, compound identification, and targeted quantitation. Adding SLIMS extends the same level of precision and control to everything that happens before and after your PFAS analysis—from order intake to reporting—creating an EPA-compliant total solution.


SLIMS + MassHunter: Stronger together

Delivering defensible PFAS analysis results means following EPA method requirements in every step. Methods like 533, 537.1, 1633, and 8327 require rigorous documentation and automated workflows to reduce risk and preserve method integrity.

Integrating SLIMS with MassHunter creates a comprehensive solution that completes your PFAS testing workflow. SLIMS provides sample tracking, inventory management, digital protocols and reporting—all in one intuitive platform that connects seamlessly with MassHunter. This solution transforms your existing triple quadrupole LC/MS setup into a fully automated, compliance-ready operation that boosts operational efficiency, ensures data integrity, and supports regulatory compliance.






Key integration benefits



Ready-to-deploy workflows for methods 533, 537.1, 1633, and 8327 can be implemented within days.




SLIMS generates sample sheets in MassHunter format and transfers them automatically to the MassHunter sequence where results are captured. The results are automatically imported back to SLIMS and linked to the correct samples and workflows. This eliminates manual errors, saves valuable time from analysis to review, and supports traceability across the entire process.

SLIMS offers flexible, real-time dashboards and reporting tools that provide a clear overview of lab operations. Users can track throughput, turnaround times, and performance metrics at a glance—empowering data-driven decisions and continuous improvement.

SLIMS functions as a full laboratory execution system (LES), guiding users through intuitive, SOP-driven workflows. It ensures full traceability with audit trails and connects seamlessly with instruments and inventory systems.

PFAS-specific protocols and step-by-step guidance simplify training and reduce implementation time.

SLIMS comes pre-loaded with PFAS testing supplies to track everything from air, water, and solid samples to standards and analytes. Out-of-range results are flagged against preconfigured analytical methods based on EPA 533 for drinking water and EPA 1633 for air and solid samples.




Your complete PFAS solution provider

Agilent is the only supplier that provides start-to-finish solutions that address PFAS analysis.


Industry-recognized PFAS analysis expertise that includes training, service, and support


Complete PFAS solutions for EPA methods 533, 537.1, 1633, and 8327


One-stop shop for instruments, software, applications, consumables, and ongoing support


How Sanexen partners with Agilent for PFAS cleanup

Sanexen, an environmental remediation company, has partnered with Agilent to tackle PFAS contamination. Agilent's cutting-edge technologies have streamlined Sanexen's workflow, enabling rapid and accurate data delivery. This collaboration aims to develop customized, cost-effective solutions for PFAS remediation worldwide through tailored solutions and expert support to deliver precise data swiftly and effortlessly. Watch Sanexen’s approach to efficient PFAS cleanup.

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Frequently asked questions

Why is it important to have a lab management system for PFAS analysis that's compliant with EPA Good Laboratory Practices (GLP)?

Testing for PFAS in water is complex, both in the methodology required and the regulatory framework within which testing is performed. Federal scrutiny of the PFAS contamination issue is increasing, and it is likely that substantial budgetary resources will continue to be devoted to assessing and mitigating public health risks associated with PFAS. Continuing to operate as a trusted analysis lab in this sector is going to require rigorous attention to process documentation, data integrity, and visibility. These are among the many strengths of a seamless data workflow management solution such as SLIMS.

Is my lab ready to deliver results for PFAS testing?

The requirements for EPA GLP are stringent and can leave you juggling all your different sources of laboratory data (SOPs, lab notebooks, chain of custody forms, and more). SLIMS helps manage every aspect of sample data management from logging chain of custody to simplifying the complexities of sample prep through step-by-step guidance and making sure all aspects of sample history are easily retrieved. With the amount of public and private interest in PFAS testing and tightening of regulations, labs cannot afford not to have an intelligent lab management solution like SLIMS.

Can I readily access the metadata needed to show sample history to auditors—what was done, when, where, and by whom?

The amount of data associated with your samples can be vast, no matter how large your testing operation may be. SLIMS helps you manage and access large volumes of data, making sure you know everything related to your samples, so that you can respond to audit requests and take important actions quickly.

Where are the potential bottlenecks in my workflow? When can my customers expect their results?

With SLIMS, you'll get answers quickly. At-a-glance graphical dashboard view of your samples helps you accurately estimate workflow timings and make quick business decisions.

If incorrect sample information gets entered, am I alerted fast enough to minimize retesting?

SLIMS tracks and flags errors so adjustments can be made quickly – no need to manually review multiple times. Efficient tracking allows for timely retesting (if needed) and prevents less experienced users from entering incorrect information that might compromise the quality of the results.

Can I quickly get answers related to every step of my PFAS testing workflow?

Yes. Encompassing the full breadth of Agilent’s industry-leading expertise in PFAS testing, SLIMS provides a comprehensive, end-to-end workflow with global traceability—from the initial customer request, through sample prep and analysis, to final delivery of the COA.

How do I ensure that sample analysis was performed according to the SOP and with all the necessary approvals?

SLIMS walks you step-by-step through the workflow: select the right instrument for each task (and ensure that it is calibrated); automate the record keeping of solvents and consumables, including manufacturer information, quantities, lot numbers, and expiration dates; all while keeping the recording and validation of results simple and compliant.