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Sample Filtration

The Captiva sample filtration portfolio includes products for physical and chemical filtration. Chemical filtration products, such as Captiva EMR with Carbon S and Captiva EMR-Lipid, feature a sorbent for the removal of unwanted matrix interferences.

Both Captiva EMR-Lipid and Captiva EMR with Carbon S can be adopted after typical extraction methods, such as QuEChERS extraction, solvent/liquid-liquid extraction, and protein precipitation. They provide highly selective and efficient sample matrix removal with minimal impact on target analyte recoveries.

Advantages of using Captiva EMR chemical filtration include improved analyte recovery and reproducibility, reduced matrix effect, and cleaner chromatographic background which improves data quality and reduces reruns. Captiva EMR products also improve instrument sustainability with less instrument downtime. Compared to commonly used methods, Captiva EMR chemical filtration provides a more simplified workflow, saves analyst time and effort, and improves the overall productivity.

Captiva physical filtration products utilize a porous membrane and frits for the physical removal of particulates. These products include Captiva filter vials, filter plates and cartridges, and syringe filters.

These products are typically recommended for samples prior to instrument injection, especially for LC and LC/MS analysis, to prevent particulates getting into LC column and detection system. Particulate contamination can result in detection flow path blocking, column back pressure accumulation, and MS source deposition. The membranes used in the physical filtration products include typical filter membrane from hydrophilic to hydrophobic membranes, glass fiber and depth filter, and common membrane pore sizes for each type of membrane.

In addition to traditional syringe filters, Agilent offers an extensive line of filter vials. Captiva filter vials, also available in pre-slit options, improve ease of use with less accessories needed and less sample transfer. Built with a unique nondrip (ND) membrane, Captiva ND plates allow for solvent-first protein precipitation using methanol or acetonitrile. Captiva’s unique dual filter design offers fast uniform flow while avoiding sample loss and filter plugging. Captiva ND filtration products support a convenient in-well protein precipitation workflow, making it much more streamlined and easier to conduct. Our 96-well plates are perfect for high-throughput, automated, in-well protein precipitation. The benefits of Captiva physical filtration include optimal instrument performance, reduced system downtime, extended column lifetime, and greater sample integrity.

Sample Filtration

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Featured Tools

Captiva Syringe Filter Selector Tool

The Captiva Syringe Filter selector tool helps you find the best syringe filter to suit your sample prep needs.

Solid Phase Extraction (SPE) Selector Tool

The SPE Selector Tool helps find the best SPE based on your application, SPE format, sample volume and bed mass.

QuEChERS Selector Tool

QuEChERS eSelector provides extraction and dispersive kit recommendations for pesticides in fruit and vegetables.

Featured Customer Testimonials

Raúl Vigas

CEO, J·Vigas

The SPME Arrow – Intuvo GC – MS/MS system incorporates maximum precision coupled with a speed that is not achieved with any other technology. According to the studies of J·Vigas, there is no other equipment on the current market for the analysis of TCA in wine stoppers that gives such reliable results in 5 minutes.

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Agilent's Bond Elut PFAS WAX Named 2023 Top Product by Environment+Energy Leader

Agilent won a 2023 Environment+Energy Leader Award for Bond Elut PFAS WAX SPE Cartridges that improve efficiency in testing for PFAS substances, the so-called ‘forever chemicals.’ Bond Elut PFAS WAX enables scientists to confidently isolate PFAS from drinking water, wastewater, soil, sludge, tissues, and food. “The presence of PFAS chemicals in our daily lives is a grave concern,” the judges wrote, “making any technology that aids in their removal from the environment truly lifesaving.”

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Agilent offers complete end-to-end workflows for extraction, quantification even at Ultra-trace levels, and reporting of PFAS in the environment. This includes a range of sample preparation products, HPLC columns, chemical standards, PFC-free sample containment and other HPLC supplies, Ultra-high performance liquid chromatography (UHPLC) coupled to triple quadrupole mass spectrometry, e-methods, as well as gas chromatography products for sampling and analyzing a challenging range of trace-level volatile and semivolatile vapors of PFAS in air.

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Agilent announced a highly-anticipated, complete workflow solution for targeted per- and polyfluoroalkyl substances (PFAS) analysis using the United States (US) Environmental Protection Agency (EPA) Method 1633 (3rd draft). EPA Draft Method 1633 currently analyzes 40 PFAS compounds in wastewater and soil and is a complex and labor-intensive method, relying on multiple sample preparation and analysis steps. Success in running the technique depends on careful sample handling and the appropriate sample preparation supplies and instrumentation.

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