PicoMaxx High Fidelity PCR System
The system is formulated with antibodies that inhibit polymerase activity until cycling begins, promoting high-specificity and reduced background. This formulation is ideal for high-throughput, multi-target amplification experiments.
The ArchaeMaxx advantage improves the yield of products by overcoming dUTP poisoning, which is caused by dUTP accumulation during PCR through dCTP deamination. Once incorporated, dU-containing DNA inhibits the enzyme and the ArchaeMaxx factor functions as a dUTPase, converting poisonous dUTP to harmless dUMP and inorganic pyrophosphate. PicoMaxx reliably produces high PCR product yields on a wide variety of templates up to 10 Kb.