PfuTurbo DNA Polymerase
Our PfuTurbo DNA Polymerase is a special formulation of cloned Pfu DNA polymerase and patented ArchaeMaxx Polymerase- Enhancing Factor that has been shown to increase PCR product yields up to 19 kb without affecting replication fidelity.
The ArchaeMaxx factor improves the yield of products by overcoming dUTP poisoning, which is caused by dUTP accumulation during PCR through dCTP deamination. Once incorporated, dU-containing DNA inhibits Pfu and the ArchaeMaxx factor functions as a dUTPase, converting poisonous dUTP to harmless dUMP and inorganic pyrophosphate. The PfuTurbo DNA Polymerase exhibits a lower error rate than other proofreading enzymes and a six-fold lower rate than Taq DNA polymerase.
The ArchaeMaxx factor improves the yield of products by overcoming dUTP poisoning, which is caused by dUTP accumulation during PCR through dCTP deamination. Once incorporated, dU-containing DNA inhibits Pfu and the ArchaeMaxx factor functions as a dUTPase, converting poisonous dUTP to harmless dUMP and inorganic pyrophosphate. The PfuTurbo DNA Polymerase exhibits a lower error rate than other proofreading enzymes and a six-fold lower rate than Taq DNA polymerase.
For Research Use Only. Not for use in diagnostic procedures.
