GeneMorph II Random Mutagenesis Kits produce highly uniform mutational spectra when performing error-prone PCR. This makes achieving random mutagenesis faster and easier. Alternative methods relying on Taq DNA polymerase have shown biases towards mutating As and Ts more frequently than Gs and Cs, skewing representation of random mutant libraries.
GeneMorph II kits utilize Mutazyme II DNA polymerase
a novel error-prone PCR enzyme blend with equivalent mutation rates at As and Ts vs. Gs and Cs.This method performs targeted random mutagenesis on protein domains and promoter elements, eliminating the need for specific restriction sites.
For Research Use Only. Not for use in diagnostic procedures.