The ABLE C and ABLE K strains are designed to enhance the probability of retrieving clones that are toxic to E. coli through the modulation of plasmid copy number. This copy number reduction decreases the levels of cloned gene products and enhances the probability that a toxic clone will be propagated. This pack contains both strains.
The ABLE C strain reduces the copy number of common cloning vectors by ~4-fold compared to the XL1-blue strain. The ABLE K strain reduces the copy number of common cloning vectors by ~10-fold compared to the XL1-blue strain.
For Research Use Only. Not for use in diagnostic procedures.