Kappa and Lambda mRNA CISH (Dako Omnis)

Kappa and Lambda mRNA CISH (Dako Omnis) are a set of oligonucleotide-based probes that bind to either the Kappa or Lambda immunoglobulin light chain mRNA. The probes are conjugated with fluorescein isothiocyanate (FITC) to enable detection using the Anti-FITC-AP CISH Accessory Kit (Dako Omnis) (K589911-2). When used along with this kit, plasma cells expressing kappa or lambda mRNA will exhibit dark blue/purple cytoplasmic staining. Evaluation of kappa and lambda requires that two slides are stained, one with each probe.