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Epstein-Barr Virus PNA Probe/Fluorescein

Epstein-Barr Virus PNA Probe/Fluorescein

EBV (EBER) probe is a mixture of fluorescein-labeled peptide nucleic acid (PNA) probes intended for the detection of latent EBV infection by in situ hybridization. Lymphoid tissue sections from Burkitt's lymphoma, Hodgkin's lymphoma and infectious mononucleosis as well as epithelial tissue from some oral leukoplakia cases and nasopharyngeal carcinoma have been found positive with this probe mixture. Used in conjunction with Dako PNA ISH Detection Kit (Code K5201), this probe allows detection of the two nuclear EBER RNAs encoded by Epstein-Barr virus by in situ hybridization within a single day on formalin-fixed, paraffin-embedded tissue sections. The number of tests is based on the use of 25 µL of probe per slide. This probe is also well-suited for use in flow cytometry. A procedure is available on request.

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