1290 Infinity III Evaporative Light Scattering Detector
1290 Infinity III Evaporative Light Scattering Detector
Novel PMT technology enables an extended dynamic range of four orders of magnitude for trace impurity analysis. This unique design provides excellent sensitivity, reproducibility, and flexibility for a multitude of applications.
- HPLC Detectors
Product Details
- High-sensitivity throughput - each process is enabled by real-time control during injection, with programmable software. This sensitivity delivers superb responses for all compounds down to low nanogram levels
- Peltier-cooled evaporation tube - cools to 10 to 80 °C, preventing degradation of thermally labile compounds
- Rapid heating and cooling of the evaporator tube - minimizes equilibration time and increases sample throughput
- Extended dynamic range detection technology gives four orders of magnitude, enabling analysis of samples with trace levels of impurities in a highly concentrated sample matrix, eliminating time-consuming reanalysis, recalibration, or sample preparation
- Real-time gas control - provides a uniform response across a solvent gradient that minimizes quantification errors
- Control and data collection system - compatible with many vendor platforms
- Solvent enhancement effects during gradient elution are eliminated through real-time evaporator gas programming for excellent quantification
- Low dispersion and high-speed data output rates - ideal for fast LC applications
- Superb reproducibility below 2% for reliable and accurate results
- Full DMSO transparency - keeps early eluting compounds detectable
- Application Notes
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HILIC Analysis of GLP-1 Receptor Agonists
Simultaneous measurement of GLP-1 receptor agonist active ingredient, product-related impurities, and excipients.
- Application Notes
- English
- 17 Oct 2025
- 596.14 KB
Easy Column Screening for Lipid Nanoparticle Component Analysis
In this application note, a column screening method is demonstrated for the analysis of the four components of the Pfizer–BioNTech vaccine (BNT162b2).
- Application Notes
- English
- 14 Oct 2024
- 458.42 KB
Sensitive Detection Technique for Analysis of Lipids in Liposomal Formulations Using an Agilent 1290 Infinity II ELSD
Presents a method for lipid identification from liposomal formulations using an Agilent 1290 Infinity II ELSD with a 1260 Infinity II LC.
- Application Notes
- English
- 21 May 2019
- 800.31 KB
Impurity Analysis of Aminoglycoside Antibiotic using the Agilent InfinityLab Poroshell 120 HILIC-Z with ELSD Detection
A method is presented for analysis of aminoglycosides. The highly polar compound is seperated using HILIC, and detected using ELSD.
- Application Notes
- English
- 25 May 2018
- 657.51 KB
Quantitation of Stachydrine in Chinese Motherwort (Leonurus japonicas) using HILIC
A method is developed for analysis of stachydrine from plant extract. The highly polar compound is seperated using HILIC, and detected using ELSD.
- Application Notes
- English
- 12 Apr 2018
- 670.60 KB
Analysis of Metals, Halides, and Inorganic Ions Using Hydrophilic Interaction Chromatography
A HILIC method for the separation of inorganic ions was successfully developed, and was used to quickly resolved various cations and anions of interest.
- Application Notes
- English
- 04 Dec 2017
- 1.47 MB
Analysis of a Fixed–Dose Combination Drug Using the Agilent 1290 Infinity II Evaporative Light Scattering Detector
Analysis and quantification in a single run of a fixed-dose combination drug using the Agilent 1290 Infinity II ELSD.
- Application Notes
- English
- 19 Mar 2015
- 795.45 KB
Separation of Homologous Series of Technical Detergents with the Agilent 1290 Infinity 2D-LC Solution Coupled to an Evaporative Light Scattering Detector
Separation of a homologous series of technical detergents with the Agilent 1290 Infinity 2D-LC Solution coupled to an Evaporative Light Scattering Detector
- Application Notes
- English
- 18 Sep 2014
- 297.08 KB
- FAQs
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Infinity III LC Series: Your FAQs, answered
Find answers to FAQs about InfinityLab Assist, InfinityLab Level Sensing, and InfinityLab Sample ID Reader.
- Site Preparation Checklists
- Supplemental Information
- User Manuals
HPLC/UHPLC Upgrades
Discover how you can enhance your lab efficiency and upgrade your existing HPLC/UHPLC systems and components.
Videos
Agilent Introduces New Polysorbate Cost and Time Savings Estimator
Polysorbate characterization is often complex due to degradation, making current methods time-consuming and inefficient. The AdvanceBio Surfactant Profiling HPLC column provides an innovative, time-saving solution to these challenges. By using the Polysorbate Cost and Time Savings Estimator, discover the hours and money you can save annually by implementing the AdvanceBio Surfactant Profiling column in your lab.
- 01 Jul 2025
Agilent Wins Two Scientists’ Choice Awards for Best New Analytical Product of 2024 and Excellence in Analytical Science Communication
Agilent Technologies Inc. received two prestigious Scientists’ Choice Awards: 2024 Webinar of the Year for “HPLC Made for Tomorrow: Introducing the new Agilent Infinity III LC Series” and Best New Analytical Product of 2024 for the Agilent 7010D Triple Quadrupole GC/MS System. These awards, voted on by the global scientific community, recognize Agilent's leadership in innovative technologies and impactful scientific education.
- 03 Jun 2025
Agilent introduces the Infinity III LC Series, transforming HPLC technology
Agilent Technologies launched the Infinity III LC Series, including the 1290 Infinity III LC, 1260 Infinity III Prime LC, and 1260 Infinity III LC systems. The systems feature InfinityLab Assist Technology for automation of daily HPLC tasks, system troubleshooting, and diagnostics. The new systems are designed to improve lab efficiency and reduce errors, promoting sustainability with My Green Lab’s ACT Ecolabel 2.0.
- 21 Oct 2024