Emulate any Agilent HPLC/UHPLC system
Intelligent System Emulation Technology (ISET)
ISET is available for Agilent 1290 Infinity III LC Systems and Agilent 1260 Infinity III Prime LC Systems – systems that have small dwell volume and pump technology to deliver accurate and precise mobile phase gradients. ISET can emulate the 1290/1260 Infinity III (and I), Agilent 1200 Series LC Systems, and Agilent 1100 Series instruments, as well as third-party HPLC instruments such as Waters Alliance, Waters ACQUITY, or Shimadzu Prominence.
- Instrument Control Software
Product Details
- Minimize your instrument-related costs: Reduce the number of instruments to maintain and save on lab space. With ISET, one high-performing low-dwell volume instrument can behave as at least seven different instruments. No need to maintain your old legacy LC systems.
- Prepare your lab for the future: Run your legacy methods without disruption with ISET while taking full advantage of the UHPLC speed, resolution, and sensitivity of the 1290 Infinity III LC and 1260 Infinity III Prime LC systems.
- Achieve higher productivity for method development: Speed up your method development with UHPLC performance and then fine-tune your method by emulating the target system – and be confident that the method will run as intended.
- Worry-free HPLC method transfers: If you are sending methods to partner labs, you can be proactive and see how the method will run on their LC systems. If you are a receiving lab, simply emulate the HPLC system on which the original method was developed – with a single mouse click.
- Application Notes
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Agilent 1290 Infinity II LC with ISET – Emulation of the Agilent 1100 Series LC Through Waters Empower Software
Method transfer from an Agilent 1100 Series LC to an Agilent 1290 Infinity II LC with ISET, while controlled through Waters Empower software.
- Application Notes
- English
- 09 Jan 2025
- 963.85 KB
Analysis of Paracetamol and Impurities using an Agilent 1290 Infinity II LC with ISET
Method transfer from Waters Alliance 2695 LC to Agilent 1290 Infinity II LC with ISET, while controlled through Waters Empower software.
- Application Notes
- English
- 09 Jan 2025
- 1.56 MB
Agilent 1290 Infinity II LC with ISET–Emulation of the Agilent 1100 Series Binary LC for Analysis of Tricyclic Antidepressant Drugs
Analysis of tricyclic antidepressant drugs with the Agilent 1290 Infinity II LC with ISET, emulating the Agilent 1100 Series binary LC
- Application Notes
- English
- 14 Oct 2024
- 834.38 KB
Universal Method Development for Various HPLC Systems
Universal method development for various HPLC systems using the Agilent 1290 Infinity II Method Development Solution with Intelligent System Emulation Technology
- Application Notes
- English
- 14 Oct 2024
- 1.13 MB
Analysis of Antihistaminic Drugs using the Agilent 1260 Infinity II Prime LC
Agilent 1260 Infinity II Prime LC with ISET – emulation of the Agilent 1200 Series Quaternary LC for analysis of antihistaminic drugs.
- Application Notes
- English
- 14 Oct 2024
- 768.55 KB
Seamless Method Transfer from a Waters Alliance LC to an Agilent 1260 Infinity II Prime LC using ISET
A demonstration of the straightforward analytical method transfer from the Waters Alliance 2695 LC to an Agilent 1260 Infinity II Prime LC by using ISET.
- Application Notes
- English
- 14 Oct 2024
- 1.96 MB
Fast screening of mobile and stationary phases with the Agilent 1290 Infinity LC and seamless method transfer to an Agilent 1200 Series LC using ISET
The Agilent 1290 Infinity LC System Method Development Solution was used to find optimum separation conditions for degra¬dation products of a pharmaceutical preparation.
- Application Notes
- English
- 14 Oct 2024
- 1.49 MB
Agilent 1290 Infinity Binary LC System with ISET - Emulation of the Waters Alliance 2695 LC system analyzing endocrine disruptors
This Application Note shows the emulation of the Waters Alliance 2695.
- Application Notes
- English
- 14 Feb 2014
- 935.10 KB
Agilent 1290 Infinity Binary LC System with ISET - Emulation of the Waters Alliance 2695 LC system analyzing antioxidants
This Application Note shows the emulation of the Waters Alliance 2695.
- Application Notes
- English
- 13 Feb 2014
- 950.63 KB
Seamless instrument-to-instrument method transfer of an USP/EP method from an Agilent 1220 Infinity LC to an Agilent 1290 Infinity Binary LC using Intelligent System Emulation Technology (ISET)
For the analysis of antituberculosis drugs the seamless method transfer of the USP method from the 1220 Infinity LC System to the 1290 Infinity Binary LC
- Application Notes
- English
- 14 Nov 2013
- 464.66 KB
- Article Reprints
- Technical Overviews
- FAQs
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Infinity III LC Series: Your FAQs, answered
Find answers to FAQs about InfinityLab Assist, InfinityLab Level Sensing, and InfinityLab Sample ID Reader.
HPLC/UHPLC Upgrades
Discover how you can enhance your lab efficiency and upgrade your existing HPLC/UHPLC systems and components.
Videos
Agilent introduces the Infinity III LC Series, transforming HPLC technology
Agilent Technologies launched the Infinity III LC Series, including the 1290 Infinity III LC, 1260 Infinity III Prime LC, and 1260 Infinity III LC systems. The systems feature InfinityLab Assist Technology for automation of daily HPLC tasks, system troubleshooting, and diagnostics. The new systems are designed to improve lab efficiency and reduce errors, promoting sustainability with My Green Lab’s ACT Ecolabel 2.0.
- 21 Oct 2024
Agilent Wins Two Scientists’ Choice Awards for Best New Analytical Product of 2024 and Excellence in Analytical Science Communication
Agilent Technologies Inc. received two prestigious Scientists’ Choice Awards: 2024 Webinar of the Year for “HPLC Made for Tomorrow: Introducing the new Agilent Infinity III LC Series” and Best New Analytical Product of 2024 for the Agilent 7010D Triple Quadrupole GC/MS System. These awards, voted on by the global scientific community, recognize Agilent's leadership in innovative technologies and impactful scientific education.
- 03 Jun 2025