6230C time-of-flight LC/MS (LC/TOF) system
6230C Time-of-Flight (TOF) LC/MS
Adding Agilent VacShield technology increases uptime for robust, reliable operation, even for challenging samples and complex matrices. Intuitive tools such as one-click SWARM autotune and Agilent WalkUp software enable even novice users to access powerful MS capabilities.
- Time of Flight LC/MS
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Product Details
- MassHunter software is ideal for labs requiring advanced and specialized workflows on the 6230C LC/TOF in complex research applications
- OpenLab CDS supports routine LC/MS workflows on the 6230C LC/TOF and is suitable for use in regulated environments; it is also the supported data system for the Agilent MAM solution
- Meet data integrity standards with technical controls to securely acquire, process, report, and store data in laboratories that must follow the compliance guidelines
- Maximize uptime and reduce maintenance time by 90–97% with ventless ion capillary maintenance provided with VacShield
- Reduce administrative tasks and risks while eliminating the need for LC/MS expertise with intuitive MassHunter WalkUp software
- Implement sustainable solutions with an optional dry pump that eliminates oil waste and achieves savings in energy consumption and heat dissipation; Eco Standby mode further decreases gas and energy use through scheduled settings
- Anticipate downtime or address immediate issues with instrument diagnostics, such as early maintenance feedback (EMF), that provide instrument health and status reports based on actively monitored metrics
- Run batches uninterrupted with intelligent reflex workflows that trigger automatic reinjection for carryover, saturation (above calibration results), and fast screening—so you can focus on results
- Generate expert, application-specific results every time with AI-based SWARM autotune for LC/MS systems—eliminating time-consuming, one-by-one parameter optimization to help identify optimal settings
- Detect low-level impurities in complex matrices with up to five orders of in-spectrum dynamic range and Agilent Jet Stream technology with low picogram on-column sensitivity
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Basics of LC/MS - a Primer
What is LC-MS? How does it work? Learn more about the typical parts of an LC/MS system, its basic principles of operation, types of LC/MS instruments, and LC/MS applications.
Learn More- Application Notes
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Oligonucleotide Analysis with Ion-Pairing-Free Reversed Phase Method and TOF LC/MS
Oligonucleotide analysis with ion-pairing-free reversed phase method and TOF LC/MS
- Application Notes
- English
- 26 Dec 2024
- 587.39 KB
Method Development Using Method Scouting Wizard on the Agilent 1260 Infinity Analytical SFC System with Time-of-Flight Mass Spectrometric Detection
Describes the use of the Agilent ChemStation Method Scouting Wizard in method development to separate and detect active compounds using SFC and TOF MS.
- Application Notes
- English
- 14 Oct 2024
- 1.15 MB
High-Sensitivity Oligonucleotide Analysis Using Ion-Pairing-Free HILIC and TOF LC/MS
This application note presents an ion-pairing-free method for high-sensitivity oligonucleotide analysis using TOF LC/MS and HILIC.
- Application Notes
- English
- 03 Nov 2023
- 428.77 KB
Identification of NISTmAb Charge Variants by Fully Automated CIEF/MS
Identification of NISTmAb Charge Variants by Fully Automated Capillary Isoelectric Focusing and Mass Spectrometry
- Application Notes
- English
- 27 Aug 2019
- 1.26 MB
Monoclonal Antibody Charge Variants Identification by Fully Automated Capillary Isoelectric Focusing – Mass Spectrometry
Presents the use of the Agilent 7100 CE Instrument with MS detection for direct MS determination of monoclonal antibody charge variants.
- Application Notes
- English
- 01 Feb 2019
- 2.41 MB
Separation of 15 Underivatized Saccharide and Sialic Acid USP Standards Using an Agilent AdvanceBio MS Spent Media Column with TOF MS Detection
An Agilent AdvanceBio MS Spent Media column is used to separate saccharide and sialic acid USP standards, with an Agilent 1260 Infinity II LC and TOF MS detection.
- Application Notes
- English
- 31 Oct 2018
- 718.22 KB
Rapid and Accurate Forensics Analysis using High Resolution “All Ions MS/MS”
This application note describes the use of a new technique, “All Ions MS/MS”, to rapidly screen and identify drugs of forensic toxicological interest.
- Application Notes
- English
- 01 Mar 2018
- 2.11 MB
Comprehensive Food Profiling Combining High Resolution LC/MS and GC/MS Analysis
A comprehensive untargeted approach using high-resolution LC/MS and GC/MS was applied to study differences in food compositions from distinct diets.
- Application Notes
- English
- 31 Aug 2017
- 6.10 MB
Cannabinoid Profiling and Quantitation in Hemp Extracts using the Agilent 1290 Infinity II/6230B LC/TOF system
Determine potency, and quantitatively profile the 11 most commonly targeted cannabinoids.
- Application Notes
- English
- 17 Aug 2017
- 644.06 KB
Profiling of Endogenous Metabolites Using Time-of-Flight LC/MS with Ion-Pair Reverse Phase Chromatography
A high performance ion-pair reverse-phase (IP-RP) chromatographic method has been developed for use with a time-of-flight (TOF) mass spectrometer (MS).
- Application Notes
- English
- 26 Apr 2017
- 989.19 KB
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