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CD42b, Platelet Glycoprotein Ib/RPE

CD42b, Platelet Glycoprotein Ib/RPE

Clone AN51

CD42b is a 145 kDa protein restricted to platelets and megakaryocytes. CD42a, CD42b, CD42c and CD42d form a complex in the platelet plasma membrane which serves as a receptor for von Willebrand factor and thrombin, and mediates adhesion of platelets to subendothelial matrices exposed upon damage to the endothelium. The binding sites for von Willebrand factor and thrombin lies on CD42b.

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