Anti-human CD79αcy antibodies. These single-color reagents are of value to the study of B cells.
CD79 is a transmembrane heterodimer belonging to the immunoglobulin superfamily. It comprises the two glycoproteins, CD79α and CD79β. CD79α is more strongly expressed by B cells in the follicular mantle zone than by germinal centre B cells, suggesting that activation of mature B cells downregulates CD79 expression. CD79 expression ceases around the onset of plasma cell differentiation, with only a proportion of plasma cells containing CD79.
Further information and references to relevant literature are available in the products Instructions For Use.