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CD41

CD41

ASR
Clone 5B12

Anti-human CD41 antibodies. These single-color reagents are of value to the study of platelets and platelet precursors.

CD41 is the α subunit of the CD41/CD61 complex (GPllb-llla), a calcium-dependent, non-covalently associated heterodimer. CD41 is a 135 kDa molecule, consisting of 2 peptides: a 120 kDa α chain and a 23 kDa β chain. The α chain and the β chain are linked by a single disulphide bond. The α chain contains four calcium-bindingsites and is entirely extracellular, while the β chain has extracellular, transmembrane and cytoplasmic domains. The CD41/CD61 complex appears early in megakaryocyte maturation.

Further information and references to relevant literature are available in the product’s Instructions For Use.

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