Anti-human CD3 antibodies. These single-color reagents are of value to the study of T cells.
Human TCR/CD3 is a complex structure on the lymphocyte surface. It consists of the TCRαβ or TCRγδ heterodimer and the associated CD3 complex. The CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. Further it plays an important role in the differentiation of thymocytes.
Further information and references to relevant literature are available in the products Instructions For Use.