Anti-human CD3 antibodies for use in flow cytometry. These single-color reagents are of value to the study of normal and neoplastic T cells.
CD3 is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocytes, the CD3 antigen is predominantly detected on the cell surface.
Further information and references to relevant literature are available in the products Instructions For Use.