Anti-human CD1a antibodies. These single-color reagents are of value to the study of cortical thymocytes and Langerhans' cells.
The CD1a antigen is a transmembrane α-chain non-covalently associated with ß2-microglobulin. CD1a is expressed strongly on cortical thymocytes and on a variety of antigen-presenting cells including Langerhans cells and interdigitating dendritic cells. CD1a is not expressed on early thymocytes, and is absent on mature peripheral blood T cells but intracytoplasmic expression is detected on activated T lymphocytes.
Further information and references to relevant literature are available in the products Instructions For Use.