Anti-human CD138 antibodies for use in flow cytometry. These single-color reagents are of value to the study of viable myeloma cells.
CD138, syndecan-1, is a transmembrane proteoglycan with a main cellular expression in stratified and simple epithelia. Within the hemopoietic system, CD138 is mainly confined to late stages of B-cell differentiation. CD138 expression is reduced during malignant transformation of various epithelia, and CD138 is rapidly shed by myeloma cells entering into apoptosis, making CD138 a marker of viable myeloma cells.
Further information and references to relevant literature are available in the products Instructions For Use.
For In Vitro Diagnostic Use.