CD11c belongs to a family of related heterodimeric proteins designated CD11. The CD11 family shares a common 95 kDa α -chain (CD18). In addition to the p150,95 protein, this protein family contains two other members: leucocyte function associated-1 antigen (LFA-1, CD11a) and iC3b receptor (CD11b). CD11c is expressed strongly on monocytes and weakly on neutrophil granulocytes. Natural killer cells and activated B and T cells also express CD11c .
Further information and references to relevant literature are available in the products Instructions For Use.