
CD117

CD117 has been shown to be a marker for tissue mast cells, haematopoietic stem cells, and progenitor cells in normal human bone marrow. The majority of CD117-positive marrow cells (50-70%) coexpress CD34 and comprise progenitor cells and their precursors of all haematopoietic lineages. Apart from mast cells, CD117 is essentially absent from mature haematopoietic cells.
Further information and references to relevant literature are available in the products Instructions For Use.