Anti-human CD117 antibodies for use in flow cytometry. These single-color reagents are of value to the study of acute myeloid leukemia (AML).
CD117, a membrane tyrosine kinase receptor, is encoded by the KIT proto-oncogene, also called c-kit. CD117 is expressed on 1-4% of normal bone marrow cells. The majority of positive cells (50-70%) co-expresses CD34 and comprises progenitor cells and their precursors of all hematopoietic cell lineages. The antibody is of value in the study of acute myeloid leukemia.
Further information and references to relevant literature are available in the products Instructions For Use.
For In Vitro Diagnostic Use.