Continuously monitor cell invasion and migration using the xCELLigence DP instrument with RTCA CIM plates, an electronically integrated Boyden Chamber. Obtain thousands of real-time CIM assay time points over the course of the entire experiment.
RTCA provides a quantitative readout of cell number, proliferation rate, cell size/shape, and cell-substrate attachment quality to provide a wide view on cell health and behavior.
For Research Use Only. Not for use in diagnostic procedures.
The functional unit of a cellular impedance assay is a set of gold microelectrodes fused to the bottom surface of a microtiter plate well. When submersed in an electrically conductive solution (such as buffer or standard tissue culture medium), the application of an electric potential across these electrodes causes electrons to exit the negative terminal, pass through bulk solution, and then deposit onto the positive terminal to complete the circuit.