xCELLigence RTCA HT-BioTek BioSpa8, Scientists’ Choice Awards 2024 Winner
xCELLigence RTCA HT-BioTek BioSpa8 – Screening Model
Integration of the Agilent xCELLigence Real Time Cell Analyzer (RTCA) HT instrument with the Agilent BioTek BioSpa 8 automated incubator expands the screening throughput of your xCELLigence RTCA HT instrument to up to eight 384-well E-Plates. Label-free high-throughput xCELLigence Real-Time Cell Analysis is ideal for screening viral mediated cytopathic effects (CPE), neutralizing antibodies, antibody-dependent cytotoxicity (ADCC), and compound mediated cytotoxicity.
xCELLigence Real-Time Cell Analysis uses impedance-based biosensors to continuously obtain non-invasive, label-free data on cell health, behavior, and function with high accuracy, sensitivity, and reproducibility. Integrating the BioSpa 8 Automated Incubator with the xCELLigence RTCA HT model enables live-cell analysis of up to 3,072 wells to meet high throughput sample screening needs.
xCELLigence Real-Time Cell Analysis uses impedance-based biosensors to continuously obtain non-invasive, label-free data on cell health, behavior, and function with high accuracy, sensitivity, and reproducibility. Integrating the BioSpa 8 Automated Incubator with the xCELLigence RTCA HT model enables live-cell analysis of up to 3,072 wells to meet high throughput sample screening needs.
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Product Details
Features
- The xCELLigence RTCA HT instrument with BioTek BioSpa 8 automated incubator enables live cell analysis up to eight 384-well E-plates (a total of 3,072 wells) with non-invasive and label-free real-time impedance technology
- Kinetic measurement of cell health, viability, or response to treatments with high sensitivity, accuracy, and reproducibility, provides a continuous flow of real-time data. The information gained from real-time live cell analysis goes far beyond end-point measurements
- Automated workflow allows users to simply add cells to E-Plates 384 and begin kinetic measurements at physiological conditions. The BioSpa8 Robotic Arm transfers E-Plate 384 from the incubator to the xCELLigence RTCA HT Station. Multiple E-Plates 384 are processed while unattended, saving time and hands-on labor in the lab
- Critical physiological conditions are controlled and maintained in the BioSpa8 incubator to ensure assay success. Temperature and CO2/O2 control, plus humidity monitoring in the BioSpa facilitate live cell processes, and the cradle of the RTCA HT unit is temperature-controlled, for minimal disruption of the cells
- Small footprint saves benchtop space
- User-friendly RTCA Software Pro HT-BioSpa enables simple assay setup and scheduling for both single and multiple users, real-time data visualization, and powerful data analysis for immunotherapy and virology applications
- Ideal for high throughput screening of therapeutic antibodies, drug compounds, and cytotoxicity
- Typical applications include Compound-mediated cytotoxicity assay; Viral-mediated cytopathic effect (CPE); Neutralizing antibody screening; Antiviral drug screening; Immune cell potency assay; Antibody-dependent cell-mediated cytotoxicity (ADCC) assays
How It Works
Applications
