ClearSeq Constitutional Disease Research Panels
The ClearSeq constitutional disease research panels are predefined designs for comprehensive analysis of targeted genes known to cause genetic disorders. Developed in collaboration with leading medical genetics experts, these constitutional panels provide deep coverage of targets, enabling clinical researchers to confidently identify mutations, indels and CNVs.
ClearSeq Inherited Disease
Developed in collaboration with researchers from Medical Genetics, Charite Berlin, this panel is a highly targeted design that enables comprehensive analysis of only those 2,742 genes known to cause inherited disorders. Faster time to sequencing is achieved when coupled with efficient SureSelect workflows that enable greatly reduced hybridization times. Deeper coverage of targets, whether single samples or trios even on a benchtop sequencer, accelerates answers with confident variant calling enabled by SureCall, a guided data analysis solution from raw data to categorized variants.
Compatible with SureSelect Target Enrichment System
ClearSeq Cardiomyopathy
ClearSeq Cardiomyopathy is a next generation sequencing target enrichment panel designed specifically for inherited forms of cardiomyopathy. Following a careful review of cardiomyopathy publications as well as information available from GeneReviews, an NIH online resource, 34 genes known to be associated with hypertrophic cardiomyopathy, dilated cardiomyopathy, and arrythmogenic right ventricular cardiomyopathy have been included.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ClearSeq Cardiomyopathy is a next generation sequencing target enrichment panel designed specifically for inherited forms of cardiomyopathy. Following a careful review of cardiomyopathy publications as well as information available from GeneReviews, an NIH online resource, 34 genes known to be associated with hypertrophic cardiomyopathy, dilated cardiomyopathy, and arrythmogenic right ventricular cardiomyopathy have been included.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ClearSeq Arrythmia - Made to order via SureDesign
Targeting genomic regions known to be associated with four inherited arrhythmia related heart disorders, ClearSeq Arrhythmia is a next generation sequencing target enrichment panel. Included are 20 genes known to correlate with long QT syndrome, short QT syndrome, Brugada syndrome, and catecholaminergic polymorphic ventricular tachycardia, developed from information gathered after a thorough review of publications for arrhythmia and from GeneReviews, an NIH resource. The genes associated with different types of arrhythmia are overlapping in some cases, and using ClearSeq Arrhythmia, a comprehensive arrhythmia profile can be assembled for clinical research samples.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
Targeting genomic regions known to be associated with four inherited arrhythmia related heart disorders, ClearSeq Arrhythmia is a next generation sequencing target enrichment panel. Included are 20 genes known to correlate with long QT syndrome, short QT syndrome, Brugada syndrome, and catecholaminergic polymorphic ventricular tachycardia, developed from information gathered after a thorough review of publications for arrhythmia and from GeneReviews, an NIH resource. The genes associated with different types of arrhythmia are overlapping in some cases, and using ClearSeq Arrhythmia, a comprehensive arrhythmia profile can be assembled for clinical research samples.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ClearSeq Noonan Syndrome - Made to order via SureDesign
ClearSeq Noonan Syndrome is a next generation sequencing panel designed using information from published literature and the NIH resource GeneReviews. This panel is designed to detect genetic mutations known to be associated with Noonan syndrome and related disorders such as LEOPARD, cardio-facio-cutaneous syndrome, and Costello syndromes.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ClearSeq Noonan Syndrome is a next generation sequencing panel designed using information from published literature and the NIH resource GeneReviews. This panel is designed to detect genetic mutations known to be associated with Noonan syndrome and related disorders such as LEOPARD, cardio-facio-cutaneous syndrome, and Costello syndromes.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ClearSeq Connective Tissue Disorder - Made to order via SureDesign
ClearSeq Connective Tissue Disorder focuses on inherited forms of connective tissue disorders, specifically targeting genetic variations associated with Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome, thoracic aortic aneurysm and dissection (TAAD), Stickler syndrome, Osteogenesis imperfecta and other related disorders.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ClearSeq Connective Tissue Disorder focuses on inherited forms of connective tissue disorders, specifically targeting genetic variations associated with Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome, thoracic aortic aneurysm and dissection (TAAD), Stickler syndrome, Osteogenesis imperfecta and other related disorders.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ClearSeq ICCG - Made to order via SureDesign
ICCG, International Collaboration for Clinical Genomics, is the organization formerly named ISCA, International Standards for Cytogenomic Arrays. In the ClearSeq ICCG gene panel, 180 genes as defined by ICCG have been incorporated into a novel next generation sequencing application, following the associated ICCG recommendations for design and resolution.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ICCG, International Collaboration for Clinical Genomics, is the organization formerly named ISCA, International Standards for Cytogenomic Arrays. In the ClearSeq ICCG gene panel, 180 genes as defined by ICCG have been incorporated into a novel next generation sequencing application, following the associated ICCG recommendations for design and resolution.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
ClearSeq X-Chromosome - Made to order via SureDesign
A wide variety of genetic disorders have been shown to be correlated to changes in the X-chromosome. The ClearSeq X-Chromosome panel is designed to interrogate these particular genetic changes on the X-chromosome in a new next generation sequencing kit. Together with SureCall analysis software, laboratories are now able to create a comprehensive X-chromosome mutation profile for clinical research samples in one efficient, cost-effective application.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
A wide variety of genetic disorders have been shown to be correlated to changes in the X-chromosome. The ClearSeq X-Chromosome panel is designed to interrogate these particular genetic changes on the X-chromosome in a new next generation sequencing kit. Together with SureCall analysis software, laboratories are now able to create a comprehensive X-chromosome mutation profile for clinical research samples in one efficient, cost-effective application.
Compatible with HaloPlexHS and HaloPlex Target Enrichment Systems
For Research Use Only. Not for use in diagnostic procedures