Skip to main content

실시간 세포 분석

xCELLigence 실시간 세포 분석

Agilent xCELLigence Real-Time Cell Analysis(RTCA) 기술은 강력하면서도 간단한 라이브셀 분석 도구를 제공합니다. 무표지 라이브셀 임피던스 및 이미징 어세이를 통해 세포 건강, 반응 및 기능을 지속적으로 모니터링합니다.

비침습적 바이오센서 기술은 세포 수, 세포 형태, 세포 기질 부착 품질, 및 세포 장벽 기능에 대한 정량적 판독 결과를 제공합니다. 세포 부착, 세포 증식, 약물/바이러스/세포 매개 세포 독성, 줄기세포 분화, 세포 장벽 기능 형성/파괴, GPCR 반응, 세포 침입 및 이동을 포함한 다양한 생물학적 프로세스를 최소한의 노력으로 실시간 모니터링할 수 있습니다.

xCELLigence RTCA 시스템은 전통적인 세포 형태 분석을 뛰어넘는 객관적이고 감도 높은 키네틱 분석을 제공하여 세포 반응과 기능에 대한 상세한 통찰력을 제공합니다.

수정자

제품

|
|

알파벳순으로 정렬

필터
여과 내용 선택 도구

문의처 선택 도구를 사용하여 제품을 찾으십시오.

주요 자료

Assessing Water Cytotoxicity with an Impedance-Based, Real-Time, and Label-Free Cellular Assay

Noninvasive and continuous monitoring of the perturbation of cellular growth following exposure to the cumulative toxicants present in water samples.

Enhancing Immune Cell Cytotoxicity and Persistence Insights Using Real-Time Cell Analysis

This editorial will discuss the potency assays available for cellular immunotherapies, the regulatory criteria they must meet, and the challenges faced in measuring immune cell cytotoxicity.

Real-Time Antibody Internalization Assays with Agilent xCELLigence RTCA eSight

This application note demonstrates a robust method for performing real-time antibody internalization assays using the Agilent xCELLigence RTCA eSight combined with CypHer5E pH-sensitive dyes.

주요 비디오
맨 위로
주요 뉴스

Agilent xCELLigence RTCA 계측기는 최근 FDA 승인된 제품의 효능 평가 분석법 개발을 지원합니다

Agilent xCELLigence 실시간 세포 분석(RTCA) 기술은 Autolus Therapeutics에서 최근 승인한 CAR T 치료제 AUCATZYL의 정확성과 신뢰성 테스트를 지원합니다. xCELLigence RTCA 기술은 역가 측정법의 개발과 구현을 지원했습니다. 애질런트는 정밀하고 신뢰할 수 있는 세포 분석 기능을 제공함으로써 견고한 분석법을 확립하려는 Autolus의 노력을 지원했습니다.

Agilent Wins Two Scientists’ Choice Awards for Drug Discovery and Development Products

The Agilent xCELLigence RTCA HT-BioTek BioSpa 8 integrates the xCELLigence Real-Time Cell Analyzer (RTCA) HT instrument with the BioTek BioSpa 8 automated incubator to expand the screening throughput of your RTCA HT instrument to eight 384-well plates.

주요 교육 및 이벤트

Advancing the Boundaries of Real-Time Live Cell Analysis

Watch our on-demand webinar to explore multiplexed real-time cellular analysis using Agilent xCELLigence RTCA technology.

E 세미나/교육

In Vivo DNA-launched Bispecific T Cell Engager Targeting IL-13Ra2 Controls Tumor Growth in an Animal Model of Glioblastoma Multiforme

Immuno-oncology research is changing the landscape of cancer treatment by harnessing the immune system to attack cancer cells. These immunotherapies utilize both the adaptive and innate arms of the immune system, playing a pivotal role in a host’s defense against tumors. Join the Agilent Immuno-Oncology webinar series and learn how experts in the field are making groundbreaking discoveries and taking steps towards a cancer-free world. Glioblastoma is an aggressive tumor with poor survival rates. Bispecific T cell engagers (BTEs) against different cancers are in various stages of clinical development. Toxicity resulting from cytokine release syndrome and the short half-life of BTEs, which necessitates continuous infusion—complicating delivery and increasing costs—are major challenges in the field. Here we describe the development of in vivo DNA-launched BTEs (dBTEs) with highly focused targeting of interleukin-13 receptor a2 (IL-13Ra2), a glioblastoma cell-surface target. We developed 4 BTEs targeting 2 epitopes of IL-13Ra2 and studied how heavy-light chain orientation affects BTE function. The dBTEs induced T cell activation, cytokine production, and tumor cytolysis in the presence of IL-13Ra2+ tumor cells, but we observed unique patterns of immune activation. We found a strong correlation between granzyme B secretion and dBTE-induced cytolysis of specific and nonspecific tumors. We down-selected dBTE PB01-forward based on lower cytokine induction profile and highest activation specificity. In vivo, dBTE PB01-forward demonstrated an improved half-life versus intravenous recombinant BTE delivery. In an orthotopic glioblastoma model, dBTE PB01-forward controlled tumor growth, improving animal survival, supporting the hypothesis that the blood-brain barrier does not affect the function of systemically delivered dBTE. Further study of PB01-forward for targeting glioblastoma and other IL-13Ra2+ cancers is warranted.
E 세미나/교육

Accelerating Antibody Therapeutics Development Webinar

Dr. Tsourkas describes how pAbBDs can accelerate the development of antibody-drug conjugates, allows for the exploration of new therapeutic paradigms.
E 세미나/교육

Identifying Regulatory Mechanisms in Cancer Metastatic Processes with an Integrated Multi-omics Approach

Identifying Regulatory Mechanisms in Cancer Metastatic Processes with an Integrated Multi-omics Approach
E 세미나/교육

0 제품 선택.

모두 제거