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1 - 20 of 4562 results
We found Product Overviews for
Critical Quality Attributes Titer Determination compendium
| Chinese (Simplified) (China) | Complete (PDF) |
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An Integrated Workflow for Intact and Subunits of Monoclonal Antibody Accurate Mass Measurements
| Chinese (Simplified) (China) | Complete (PDF) |
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| Japanese (Japan) | Complete (PDF) |
In this application note, we show an alternative analysis of LMW species of mAbs based on the excellent performance of the 1290 Infinity II Bio LC and the PEEK-lined PLRP-S column.
| Chinese (Simplified) (China) | Complete (PDF) |
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| German (Germany) | Complete (PDF) |
| Spanish (Spain) | Complete (PDF) |
| Japanese (Japan) | Complete (PDF) |
| Italian (Italy) | Complete (PDF) |
| Korean (Korea) | Complete (PDF) |
| French (France) | Complete (PDF) |
A versatile Agilent Bio-Monolith Protein A column analyzed an optimized recombinant mAb manufactured with desired structural characteristics.
An Agilent Bio-Monolith Protein A column determined recombinant mAb titer and was used to enrich µg amounts of antibody for further structural characterization by MS.
Join Our Webinar: Efficient Protein Analysis with Cary 3500 UV-Vis Spectroscopy
Join Our Webinar: Efficient Protein Analysis with Cary 3500 UV-Vis Spectroscopy
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Join us for an insightful webinar on May 28-29, 2025, titled "Simplify Your Workflow: Rapid and Efficient Protein Analysis with UV-Vis Spectroscopy." This event will feature Dr. Aveline Neo, a Solution Scientist at Agilent Technologies, who will showcase Cary 3500 UV-Vis Spectrophotometer capabilities in streamlining protein analysis workflows. Discover how the Cary 3500 UV-Vis Multicell Peltier enables rapid and precise determination of protein extinction coefficients at 280 nm, enhancing the efficiency and accuracy of your analyses. The webinar will also introduce exciting new software enhancements to the Cary UV Workstation , including one-click extinction coefficient calculations and optimized workflows for simultaneous measurement of multiple samples. Built-in calibration curves for monoclonal antibody (mAb) concentration estimation will be highlighted, providing valuable insights for researchers working with proteins, peptides, or biopharmaceuticals. This event is ideal for analytical scientists, technicians, researchers, quality control specialists, and laboratory managers looking to enhance their analytical efficiency and accuracy. Don't miss this opportunity to learn about the latest advancements in UV-Vis spectroscopy and how the Cary 3500 UV-Vis can benefit your workflows. Register now to secure your spot and take advantage of this valuable learning experience.
ProteoAnalyzer
ProteoAnalyzer
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User Manuals Title Type ProteoAnalyzer System Manual User Manual ProSize Data Analysis Manual for Protein User Manual Capillary Array Installation on Parallel Electrophoresis Instruments Knowledge Portal Article Quick Guide Title Type Protein Broad Range P240 Kit Quick Guide Application Resources and Technical Notes Title Type Dependable Denaturing Protein Electrophoresis Agilent ProteoAnalyzer system Brochure Protein Sizing and Quantification With the Agilent ProteoAnalyzer system Technical Overview Quality Analysis Using the Agilent ProteoAnalyzer System and SDS-PAGE: A comparison of sizing and quantification performance Technical Overview Analysis of NIST Antibody on the Agilent ProteoAnalyzer System Technical Overview Analysis of Protein Size and Concentration using the Agilent ProteoAnalyzer and Agilent 2100 Bioanalyzer Systems Technical Overview Protein Sizing with the Agilent ProteoAnalyzer System Technical Overview Best Practices for Protein Analysis with the Agilent ProteoAnalyzer System Technical Overview Analysis of Model Proteins Using the Agilent ProteoAnalyzer System and a µCE-SDS System Technical Overview Complementary Methodologies for Analysis of NISTmAb Impurities Application note Analysis of Protein Crude Lysates on the Agilent ProteoAnalyzer System Technical Overview Quality Control of Protein Expression and Purification Steps with the Agilent ProteoAnalyzer System Application Note Fluorescence vs. UV Detection: Comparing Two CE-SDS Systems Using NISTmAb Application Note Empowering High-Throughput Proteomics Workflows with the Agilent ProteoAnalyzer System Application Note Protein Purity Assessment Across the Broad Linear Dynamic Range of the Agilent ProteoAnalyzer System Application Note Accurate mAb Sizing Using the NIST mAb as a Ladder for the Agilent ProteoAnalyzer System Application Note Antibody-Drug Conjugate (ADC) Analysis with the Agilent ProteoAnalyzer System Application Note Software Title Type Software Download for Agilent ProteoAnalyzer Agilent ProSize Data Analysis Software Revision ProteoAnalyzer Controller Software Revision Software ReadMe file Recommended PC Setup ProteoAnalyzer Recommended PC Setup Consumables and Supplies Title Description Capillary Array 12 capillary array ProteoAnalyzer Parts and Accessories Tray carrier, tube cap, gel bottle cap replacement and 96 deep-well trays Tray adaptor for customers wanting to use 12 vial strip tubes is available For Research Use Only.
Application Note: Cary 630 FTIR for the Fast and Easy Assessment of Protein Secondary Structures
Application Note: Cary 630 FTIR for the Fast and Easy Assessment of Protein Secondary Structures
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Proteins carry out a wide variety of molecular functions, due in part to their ability to fold into almost unlimited conformations. In return, their effectiveness in performing these functions is highly dependent on the protein’s structure. It is therefore key for life science researchers and developers of new protein-based therapeutics to have a good understanding of the protein’s structure and structural changes. Technologies that were traditionally used for protein structure analysis include: Circular dichroism (CD) X-ray crystallography Nuclear magnetic resonance (NMR) spectroscopy These techniques usually produce highly accurate results but suffer from sampling and operational challenges: Complex and time-consuming sample preparation Limited to certain sample forms (e.g., crystalline proteins) Requires highly trained operators In a recent application note, researchers at the Agilent Global Solution Development Center (GSDC) in Singapore demonstrated how the Agilent Cary 630 FTIR spectrometer with the Agilent MicroLab software can be used to quickly and easily estimate the secondary structure of proteins in solution. Protein Secondary Structure Estimation Using the Agilent Cary 630 FTIR Spectrometer (5994-7808EN) The sample measurements were completed in a few minutes, and the data analysis was straightforward—only taking a few minutes, without requiring highly skilled technical staff. This methodology can complement traditional technologies as it opens the way to fast secondary structure analysis for: rapid quality check of protein samples, comparative studies between similar proteins, comparative studies between protein therapeutics and their biosimilars, quickly assessing the impact of post-translational modifications on structure, correlating structural changes with functional changes observed with other analytical techniques. Download the application note for full details: Protein Secondary Structure Estimation Using the Agilent Cary 630 FTIR Spectrometer
AssayMAP User Group Talks Cambridge, MA
AssayMAP User Group Talks Cambridge, MA
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Dear AssayMAP Community, We spent an amazing day at the Broad Institute sharing great stories and achievements using the AssayMAP Bravo. What made this event very unique were the highly interesting and engaging talks covering various topics to analyze and characterize proteins. A big thank you to all the presenters and the willingness to share the outstanding work! Please find attached the slide decks covering the following topics Phosphoproteomics in low-input cellular models: A fully automated, high-throughput MS-based assay Kat De Ruff, Scientist, The Broad Institute Using AssayMAP for TMT Labeling of Peptides for Peptide Analysis Bekim Bajrami, Scientist, Biogen Idec Overcoming biologics discovery and engineering challenges with throughput Noah Pefaur, Abbvie Fast, sensitive and selective PTM-peptide immunoprecipitation with the AssayMap Bravo Alissa Nelson, Research Scientist, Cell Signalling Technologies Rapid Low-level Identification and Quantitation of Host Cell Proteins Chris Colangelo, LCMS Product Specialist, Agilent Attachments: community.agilent.com/.../3225.Rapid-low_2D00_level-Identification-and-Quantification-of-Host-Cell-Proteins-Chris-Colangelo.pdf Rapid low-level Identification and Quantification of Host Cell Proteins Chris Colangelo.pdf community.agilent.com/.../2475.Fast-Sensitive-and-selective-PTM_2D00_Peptide-Immunoprecipitation-with-AssayMAP-Alissa-Nelson.pdf Fast Sensitive and selective PTM-Peptide Immunoprecipitation with AssayMAP Alissa Nelson.pdf community.agilent.com/.../4061.Overcoming-biologics-discovery-and-engineering-challenges-with-throughput-Noah-Prefaur.pdf Overcoming biologics discovery and engineering challenges with throughput Noah Prefaur.pdf community.agilent.com/.../4010.Using-AssayMAP-for-automated-TMT_2D00_labeling-of-Peptides-and-Peptide-Analysis-Bekim-Bajrami.pdf Using AssayMAP for automated TMT-labeling of Peptides and Peptide Analysis Bekim Bajrami.pdf
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Enables multiple workflows in biopharmaceutical characterization
Intact Protein Approach to Exoglycosidase Sequencing / N-Glycan Analysis of Proteins
Easy-to-use and fully integrated method for determination of DAR values for ADCs
| Korean (Korea) | Complete (PDF) |
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Using Automated Affinity Purification, LC/MS analysis, and Novel DAR Calculation Software
| Korean (Korea) | Complete (PDF) |
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| Chinese (Simplified) (China) | Complete (PDF) |
Series of webinars focused on pharmaceutical discovery, development, manufacturing, and quality control and has sample-to-data solutions that work together seamlessly.
Column User Guide for Agilent AdvanceBio Glycan Mapping Columns. Application-specific columns designed for the characterization of protein glycosylation.
This application note demonstrates how the xCELLigence system can run GPCR assays without expressing additional reporter proteins.
Agilent-NIST mAb application compendium chapter Glycan Analysis.
In this chapter, the Agilent solution suitable for the measurement of peptide mapping is discussed in the context of characterizing NISTmAb.
Agilent-NIST mAb application compendium chapter Intact Analysis.
User manual for GP96NG-PC Rapid N-Glycan Preparation with InstantPC
| English (United States) | Complete (PDF) |
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| English (United States) | Complete (PDF) |
| English (United States) | Complete (PDF) |
Demonstration of robust and reliable peptide mapping and characterization of post-translational modifications in mAbs using an AdvanceBio Peptide Plus column
| Chinese (Simplified) (China) | Complete (PDF) |
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Analysis using BioPack Triple-Resonance 3-D pulse sequences that permit “linked” acquisition of indirect dimensions for 3-D protein structuring.
Identification of monoclonal antibody mutation sites using the 1290 Infinity II 2D-LC solution with 6530 Q-TOF LC/MS.
| English (United States) | Complete (PDF) |
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Ultimate flexibility for more informed decisions. One instrument and multiple workflows for biopharma.
| Korean (Korea) | Complete (PDF) |
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| Japanese (Japan) | Complete (PDF) |
| Chinese (Simplified) (China) | Complete (PDF) |