WinGPC Software

WinGPC Software and full GPC/SEC instrument control

Reliable, User-Friendly GPC/SEC Analysis

  • Agilent WinGPC is a powerful, standalone gel permeation and size exclusion chromatography (GPC/SEC) software platform designed to streamline GPC/SEC and macromolecular analysis. It offers comprehensive instrument control, seamless data acquisition, and robust evaluation tools&mdash;all in one intuitive interface. <br><br>Supporting advanced workflows like light scattering, viscosity, 2D-GPC/SEC, and mass spectrometry data integration, WinGPC adapts to your analytical needs. With flexible editions that include compliance supporting features, this GPC/SEC software ensures reliable, scalable performance for research and regulated environments alike.
  • Intuitive operation: Simplified user interface gives full control and shows all important parameters and results simultaneously during GPC/SEC analysis
  • Reliable automation: Automated (re)calibration and advanced data evaluation with full GPC/SEC instrument control simplify any GPC/SEC workflow
  • Flexible and comprehensive analysis: Dedicated workflow add-ons for specialized GPC/SEC applications like multi-angle light scattering (MALS) detection or 2D-GPC/SEC can be added to the main software at any time
  • Precise and accurate results: Unique algorithms, comparison overlays, and optimized workflows
  • Saved time and costs: Overlaid injection feature increases efficiency and reduces solvent consumption

For Reliable, User-friendly GPC/SEC Analysis

Full standalone GPC/SEC instrument control, data acquisition, and data evaluation capabilities.

Screenshot of Agilent WinGPC chromatography software showing instrument settings, molecular mass distribution, chromatogram traces, and elugram charts.

Overview

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Overview

Features

User-friendly interface

Enables users to control instruments and view results in one streamlined view.

Smart automation tools

Automates calibration and data evaluation to simplify complex workflows.

Modular workflow options

Enables specialized GPC/SEC analysis with add-ons like MALS and 2D-GPC/SEC.

High-accuracy algorithms

Ensures precise results with optimized overlays and comparison tools.

Overlay injection mode

Boosts lab efficiency by reducing solvent use and speeding up analysis.
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Why WinGPC Software for GPC/SEC analysis?

Explore the capabilities of WinGPC software for accurate GPC/SEC analysis, molecular characterization, compliance support, and control of Agilent GPC/SEC instrumentation.

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Software capabilities

Agilent WinGPC screenshot showing light-scattering analysis of a polystyrene sample, with chromatograms, molecular-weight distributions, calibration plots, and colored data curves; a graph options menu is open.

Advanced detection: Comprehensive Light Scattering and Viscometry Analysis

WinGPC delivers advanced GPC/SEC characterization with integrated light scattering and viscometry workflows. The software combines concentration, multi-angle light scattering, and viscometer data to determine absolute molecular weight distributions, intrinsic viscosity, radius of gyration (Rg), and polymer structure information. Intuitive visualization, guided detector setup, and comprehensive reporting accelerate the analysis of polymers, biopolymers, and other macromolecules.

Agilent calibration software displaying a polystyrene molar-mass calibration curve, data table, elution-volume chromatograms, and overlaid molar-mass distribution peaks.

From elution volume to molecular weight: calibration in WinGPC

The WinGPC Software offers powerful calibration management with interactive calibration curves, flexible fitting models, and comprehensive standard evaluation. Real-time visualization of chromatograms, molecular weight distributions, and calibration performance helps ensure data quality while supporting conventional, universal, light scattering, and viscometry-based analyses for confident polymer characterization.

Agilent chromatography interface with an RI chromatogram showing four peaks, overlaid by WingPC Logbook and Authentication windows for GPC/SEC Admin e-signature submission.

Compliance edition with audit trails and user groups

WinGPC supports compliance with FDA 21 CFR Part 11 requirements through features such as audit trails for the administration console, sessions, instruments, and injections. User groups, roles, and privileges can be configured to support different levels of user access.

Agilent WinGPC Instrument 1.0 settings window showing pump, detector, autosampler, and refractive-index detector controls with live readings, setpoints, and system action buttons.

Instrument control

Full support for Agilent GPC/SEC systems, including all multidetector modules, the Agilent 1260 Infinity II Multi-Angle Light Scattering Detector, and the Agilent 1260 Infinity II GPC/SEC Column Thermostat.

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How it works

Agilent WinGPC Workstation Client-Server Edition interface for advanced GPC/SEC polymer analysis software.

WinGPC Workstation

WinGPC is a complete and flexible GPC/SEC software solution made by chromatography experts for both GPC/SEC experts and novices. It is designed specifically for analysis of the heterogeneity of macromolecules and distributions.​ WinGPC offers unparalleled functionality and calibration options to enhance your lab productivity.

WinGPC compliance support

To fulfill the requirements for analytical quality and efficacy, workflows including software need to be in line with federal regulations. Accordingly, WinGPC software is designed to help to maintain compliance with FDA 21 CFR Part 11 requirements. Software features—such as data integrity, accuracy, user authorization, and traceability—help make regulatory compliance easier for analytical labs that use macromolecular chromatography.

Agilent chromatography interface with an RI chromatogram showing four peaks, overlaid by WingPC Logbook and Authentication windows for GPC/SEC Admin e-signature submission.
Scientist operating an Agilent GPC/SEC system in a laboratory environment.

More sustainable operation in your GPC/SEC analysis

Intelligent method setup without compromising the analytical outcome is the goal of sustainability- and efficiency-driven optimization in the analytical lab.​

With the WinGPC software overlapping injection feature, up to 30% of overall time can be saved by reducing the redundant time between injections coming from column interstitial volume. Overlapping injection can be applied with all types of columns—independent of length and diameter—keeping resolution and analytical conditions the same.

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Discover the software technology that WinGPC brings to your GPC/SEC analysis

Multidetector integration and unified data handling

WinGPC supports multidetector configurations, including:

  • Refractive index
  • UV/Vis
  • Light scattering
  • Viscometry

This allows for acquisition and unified analysis of data from multiple detectors, enabling absolute molecular weight determination, branching analysis, and intrinsic viscosity calculations crucial for advanced polymer characterization in GPC.

Powerful calibration and evaluation

WinGPC includes sophisticated calibration tools to allow users to accurately:

  • Determine molecular weight distributions
  • Apply complex calibration models
  • Evaluate polymer architecture and composition

Making it ideal for both routine QC and advanced R&D in polymer science.

Customizable workflows

The software is designed with a modular structure, allowing users to adapt the system to their needs:

  • Dedicated modules for data acquisition, evaluation, reporting, and database management
  • Support for multiuser environments and networked installations
  • Optional compliance supporting features
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Applications

Close-up of fingers holding polymer pellets used in laboratory materials and analytical applications.

GPC/SEC applications - what you should know when you need to analyze polymers, biopolymers, and proteins

Seven sections in this eBook describe various powerful gel permeation and size exclusion chromatography applications and use cases in detail when you need to analyze polymers, biopolymers, and proteins.

Read application series

Preventing waste with overlapping injection function in WinGPC

Agilent WinGPC Overlapping Injection function enables a sample to be injected before the previous sample has completely eluted, saving solvent and analysis time.

Read technical overview

Laboratory scientist conducting analytical testing using a GPC/SEC system.
Laboratory scientist performing chromatography data analysis.

Guided detector setup for all detector types using WinGPC

To evaluate measurements and obtain correct results using light scattering detectors or viscometers, several factors must be determined. This note describes how necessary parameters for all detectors and combinations can be determined using the Agilent WinGPC Software detector setup dialog box.

Read technical overview

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Documents & support

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Method development and analytical services for GPC/SEC and macromolecules

Develop custom analytical and consulting services with our GPC/SEC, IPC, and 2D experts

Agilent GPC/SEC Analytical Services is a selection of contract analysis and method development services with consulting opportunities for all industries working with macromolecules and polymers. The services we provide give you the opportunity to outsource your molecular analysis, gain insights on how to advance your analysis and research, and work directly with our specialists to develop a suitable analytical method.

Find out how to send samples

GPC/SEC analysis with conventional calibration

Agilent Analytical Services will perform contract analysis to determine the absolute molar masses of your macromolecular samples using conventional GPC/SEC.

Find out more

GPC/SEC analysis with light scattering/viscosity detection

Performing contract analysis on your macromolecular samples using GPC/SEC with light scattering and viscosity detection when no appropriate standards are available to derive molar masses.

Find out more

GPC/SEC analysis according to standardized methods

GPC/SEC contract analysis of macromolecular samples following either standard methods provided by our customers, or existing national and international guidelines such as REACH. We also provide characterization data for product registration and can perform monograph testing.

Find out more

Advanced macromolecular characterization

Contract analysis for the characterization of complex structured macromolecules. We perform analyses regarding molar mass, structure, branching, or chemical composition distribution on almost any macromolecule using a variety of methods. Deformulation of complex mixtures can be performed by 2D chromatography.

Find out more

Method development services for macromolecules

GPC/SEC method development services, enabling you to collaborate with an Agilent specialist to create a macromolecular analysis method that is tailored to your analytical needs. Our specialists will also help you validate the method, transfer it to your laboratory, and can offer consulting on characterization of macromolecules.

Find out more

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Frequently asked questions

What is WinGPC software?

WinGPC is a dedicated GPC/SEC software solution made by chromatography experts to support a huge variety of GPC/SEC workflows. It can be flexibly upgraded with specific add-ons to achieve even more advanced functionality, including light scattering detection.

Does WinGPC Software support light scattering detectors like MALS?

Yes, the WinGPC light scattering and viscosity add-on adds workflow support and calculation capabilities for all Agilent light scattering detectors, including the 1260 Infinity II Multi-Angle Light Scattering Detector.

Does WinGPC software support standard LC workflows?

Yes, WinGPC comprises an HPLC mode that allows for performing liquid chromatography experiments and data evaluation.

Do I need an additional Chromatography Data System for instrument control or data acquisition?

No, WinGPC is a macromolecular chromatography data system, developed as a standalone software suite that is capable of covering everything from instrument control and data acquisition to analysis and reporting.

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Tools

Positions Agilent as a strategic partner by offering tools and insights for lab success.​

Think Big: See What’s Possible with the Largest GPC/SEC Portfolio

Agilent offers a complete portfolio of GPC/SEC instruments, columns, supplies, software, and services for macromolecular characterization.

GPC/SEC Column Selector Tools

Choose your column with Agilent GPC/SEC column selector tools and select from mobile phase, application USP designation, or EP monograph.

HPLC/UHPLC upgrades

Discover how you can enhance your lab efficiency and upgrade your existing HPLC/UHPLC systems and components.

Essential supplies guide

Discover the right supplies for your InfinityLab LC Series instrument to achieve peak performance and optimize your LC workflow.

LC application finder

Browse all LC application notes and technical overviews in one place.

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Fosters skill-building through expert-led and self-paced content

Use and Optimization of WinGPC UniChrom Macromolecular CDS

This course will cover method concepts, file and data structures, instrument configuration, sequence management, and sample and data analysis.

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Training
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1-Day
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Classroom

Techniques of Gel Permeation and Size Exclusion Chromatography

This training course provides lectures and laboratory sessions for modern analysis of macromolecules using GPC/SEC.

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Training
duration
2-Days
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instructor-led

Viscometry and Light Scattering Detection Methods

This course covers aspects of advanced detection methods and instruments for determination of molar masses, sizes, and structures of macromolecules.

webinarType
Training
duration
2-Days
type
instructor-led

GPC/SEC Operation - 4 Day

Learn the basic operation of Agilent 1260 Infinity Bio-MDS liquid chromatography and GPC/SEC software, liquid chromatography, and GPC/SEC software.

webinarType
Training
duration
4-Days
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instructor-led

Agilent GPC Operation - 1 Day

Learn the basic operation of Agilent GPC/SEC liquid chromatography and GPC/SEC software.

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Training
duration
1-Days
type
instructor-led
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Agilent University

Customized training and support for your lab. Agilent University offers in-person or virtual training courses and webinars.

Financial solutions

Learn about financing options through Agilent Financial Solutions to help you acquire the equipment you deserve.

OpenLab help & learning

A portal that has user guides on how to operate the software

Virtual tech support

Live technical help directly from experts using phone, video conferencing or the Virtual Assist app.

Software service desk

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