Agilent Early Career Professor Award

Agilent congratulates Dr. Mitchell Guttman, winner of the 2015 Agilent Early Career Professor Award

2015 Focus: Contribution to the understanding and use of CRISPR/Cas or other RNA-based technologies for genome editing, control and other applications.

Mitchell Guttman, Ph.D.

Mitchell Guttman, Ph.D.
Assistant Professor
Division of Biology and Biological Engineering
California Institute of Technology
Pasadena, CA

Dr. Guttman received his PhD from the Department of Biology at MIT in 2012. He then established his lab as an independent Fellow at the Broad Institute prior to joining the faculty at Caltech in June 2013. Dr. Guttman obtained his Master's degree in computational biology and bioinformatics as well as Bachelor degrees in molecular biology and in computational biology from University of Pennsylvania in 2006.

Dr. Guttman’s graduate work at MIT and subsequently at the Broad Institute resulted in the discovery and characterization of lincRNAs, short for large intergenic noncoding RNA’s. lincRNAs perform many jobs in the cell, from regulating the plasticity of embryonic stem cells to induction and maintenance of X chromosome inactivation. Dr. Guttman discovered lincRNAs by developing novel bioinformatics methods to analyze RNA sequencing data and exploited chromatin signatures, protein binding interactions and chemical changes in the way DNA wraps around partner proteins to unveil lincRNAs mechanisms of action. His work also has elucidated a potential role for lincRNAs as key organizers of protein complexes at specific genome locations.

His current work focuses on dissecting the mechanisms that govern lincRNA localization to regulatory target sites by binding to specific proteins/protein complexes and nucleic acid sequences in order to better understand how linRNAs control gene expression programs and cell state decisions.  By exploiting the unparalleled properties of lncRNAs his work also intends to create a modular and programmable approach for mammalian cellular engineering.

Dr. Guttman has received numerous awards and recognitions for his work, including the 2012 NIH Director's Early Independence Award and was named one of Forbes magazine's "30 under 30" in science in 2014.

Purpose of Award

  • Promote and encourage excellent research enabling measurements of importance to Agilent Technologies and the world
  • Establish strong collaborative relationships between Agilent researchers and leading professors early in their career
  • Build the prominence of Agilent as a sponsor of university research

Selection Criteria

  • Significant original research contributions enabling measurements of importance to Agilent Technologies and the world
  • Outstanding potential for future research
  • Alignment with specified award focus
  • Professor completed Ph.D. or M.D. less than 10 years before January 1st of the year of the award.

Award Information

  • An unrestricted research award of $50,000 per year for 2 years to university in the professor's name
    • Option to use all or part of award to obtain Agilent products at 50% discount
    • Option to accelerate payments to facilitate procurement of equipment with list price over $100k
  • Winner is invited to make a presentation at an Agilent site (at Agilent’s expense) and presented with an engraved plaque commemorating award
  • Past and present winners’ names are posted on the Agilent website along with articles highlighting the principal academic contributions for which the awardees were selected

2016 ECPA Award

  • Award focus, instructions and deadlines will be posted in October 2015.

Past Winners

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