Agilent Early Career Professor AwardAgilent Announces the Winner of the 2014 Agilent Early Career Professor Award:
2014 focus: Contributions to the development of advanced single-cell measurement technologies for investigating molecular properties and dynamics in populations of cells
Paul Blainey, PhD
Broad Institute of MIT and Harvard
Department of Biological Engineering
Massachusetts Institute of Technology
Dr. Blainey joined the faculty of the Department of Biological Engineering at MIT and the Broad Institute of MIT and Harvard in 2012. The aim of his research program is to integrate new microfluidic, optical, and molecular tools for application in the life sciences. The Blainey lab emphasizes quantitative single-cell and single-molecule approaches, aiming to enable multiparametric studies with the power to reveal the workings of natural and engineered biological systems across a range of scales.
In his Ph.D. thesis work at Harvard University Dr. Blainey showed that protein molecules slide in persistent contact with DNA and recast the problem of lesion recognition by repair proteins in kinetic rather than thermodynamic terms. He went on to demonstrate that DNA-binding proteins track the DNA helix as they slide and discovered new classes of biomolecules with sliding activity. As a post-doc Dr. Blainey advanced the sensitivity of next-generation sequencing technology utilizing digital PCR, single cell sorting, and microfluidic whole-genome amplification technology.
At MIT and the Broad Institute Dr. Blainey is focused on technology and application development in microfluidics and single-cell genomics. His group partners with research scientists at the Broad Institute to realize new, streamlined technology platforms that dramatically improve the throughput of key workflows. Dr. Blainey is also working to create novel workflows including entirely new ways of using single-cell sequencing.
Dr. Blainey received a Bachelor of Science degree in Chemistry and a Bachelor of Arts degree in Mathematics in 2001 from the University of Washington, both cum laude. He received his Ph.D. in Physical Chemistry in 2007 from Harvard University. From 2007 to 2012 he worked at Stanford University as a post-doc in Stephen Quake's laboratory.
The purpose of the Agilent Early Career Professor Award is to:
- Promote and encourage excellent research enabling measurements of importance to Agilent Technologies and the world
- Establish strong collaborative relationships between Agilent researchers and leading professors early in their career
- Build the prominence of Agilent as a sponsor of university research
- Significant original research contributions enabling measurements of importance to Agilent Technologies and the world
- Outstanding potential for future research
- 2014 focus: Contributions to the development of advanced single-cell measurement technologies for investigating molecular properties and dynamics in populations of cells
- Professor completed Ph.D. or M.D. less than 10 years before January 1, 2014
- An unrestricted research award of $50,000 per year for 2 years to university in the professor's name
- Option to use all or part of award to obtain Agilent products at 50% discount
- Option to accelerate payments to facilitate procurement of equipment with list price over $100k
- Engraved plaque commemorating award
- Recognition on Agilent's website