Agilent Thought Leader Program

The Agilent Thought Leader Award promotes fundamental scientific advancements by contributing financial support, products and expertise to the research of influential thought leaders in the life sciences, diagnostics, and chemical analysis.

Award Recipients:

Dr. Carolyn Mountford

Dr. Carolyn Mountford
Centre for MR in Health
School of Health Sciences
Faculty of Health and Medicine
University Drive, Callaghan
NSW 2308, Australia
University of Newcastle, Australia

Dr. Mountford is a professor of radiology at The University of Newcastle Australia School of Health Sciences, and Harvard Medical School. She is the director of Newcastle's Magnetic Resonance Centre for Clinical Research and director of the Center for Clinical Spectroscopy at the Brigham and Women's Hospital in Boston. Dr. Mountford is known for her innovative work using nuclear magnetic resonance (NMR) spectroscopy technology in cancer research. (press release)

Dr. John Rabinowitz

Dr. John A. McLean
Department of Chemistry
Vanderbilt University
7330 Stevenson Center
Nashville TN 37235
Awarded: March 2014

In Vanderbilt's Department of Chemistry, Prof. McLean and colleagues focus on the conceptualization, design, and construction of structural mass spectrometers, specifically targeting complex samples in systems, synthetic, and chemical biology as well as nanotechnology. His group applies these strategies to forefront translational research areas in drug discovery, personalized medicine, and 'human-on-chip' synthetic biology platforms.

Dr. Joshua D. Rabinowitz

Dr. Joshua D. Rabinowitz
Professor of Chemistry and Integrative Genomics
Carl Icahn Laboratory, Rm. 241
Washington Road
Princeton University
Princeton, NJ 08544
Awarded: October 2013

Dr. Rabinowitz has made seminal conceptual and methodological contributions to the metabolomics field. These include the development of isotopic labeling, sample preparation, data analysis, and information visualization techniques for liquid chromatography/mass spectrometry data. (press release)

Dr. Paul B. Watkins

Dr. Paul B. Watkins
Professor of Medicine, Toxicology, and Experimental Therapeutics
Director, Institute for Drug Safety Sciences
The Hamner Institutes for Health Sciences
6 Davis Drive
Research Triangle Park, NC 27709-2137
Awarded: October 2013

Paul B. Watkins, M.D., is the Professor of Medicine, Professor of Toxicology, and Professor of Experimental Therapeutics at The University of North Carolina at Chapel Hill (UNC), and serves as Director of the Institute for Drug Safety Sciences. As an internationally recognized expert in drug safety, Dr. Watkins has extensive research experience in drug-induced liver injury (DILI), which includes basic investigation in drug metabolism and transport, clinical studies, causation assessment, and regulatory affairs. (press release)

Dr. Junying Yuan

Dr. Junying Yuan
Director of the Interdisciplinary Research Center on Biology
Chinese Academy of Science
No.345 Lingling Road
Shanghai 200032, China
Awarded: November 2013

Dr. Junying Yuan is a pioneer and leading researcher in the field of cell death. The Agilent Thought Leader award will support metabolomics and integrated biology efforts for the identification of neurodegenerative diseases biomarkers at the Chinese Academy of Science's newly established Interdisciplinary Research Center on Biology and Chemistry. (press release)

Dr. Guibin Jiang

Dr. Guibin Jiang
Director of State Key Laboratory of Environmental Chemistry and Ecotoxicology
Chinese Academy of Sciences
Haidian District,
Beijing, China
Awarded: October 2013

Dr. Jiang's research is mainly focused on analytical chemistry and environmental chemistry. His methodical and comprehensive research has resulted in significant achievements on analytical development and environmental characterization of persistent organic pollutants (POPs), and the speciation of organometallic compounds, which have contributed to the improvement and internationalization of these scientific fields in China. (press release)

Dr. Emmanuel Barillot

Dr. Emmanuel Barillot
Institut Curie
Director of Bioinformatics and Systems IT
Paris France
Awarded: August 2013

Dr. Barillot's area of work is in the development of a database of cellular signaling pathways and a visualization tool to help the pharmaceutical industry develop more effective cancer treatments. (press release)

Dr. Hashim Al-Hashimi

Dr. Hashim Al-Hashimi
J. Lawrence Oncley Collegiate Professor of Chemistry and Biophysics
University of Michigan
Dept. of Chemistry and Biophysics
Ann Arbor, MI
Awarded: March 2013

Dr. Hashim Al-Hashimi is an influential researcher in the realm of structural biology. Dr. Al-Hashimi and his team at the University of Michigan are developing advanced methods to characterize Hoogsteen base pairs — a rare form of DNA that is structurally distinct from the typical double helix — using nuclear magnetic resonance spectroscopy. Hoogsteen base pairs, named after biochemist Karst Hoogsteen, are of particular interest because of their unusual structure and biological functions. Dr. Al-Hashimi and his team believe their research could lead to significant advances in DNA-targeted drug discovery and other applications. (press release)

Dr. Ronald DePinho

Ronald DePinho, M.D.
University of Texas
President, MD Anderson Cancer Center
Houston, TX
Awarded: December 2012

Dr. Ronald A. DePinho, a world-renowned oncologist and researcher, has received an Agilent Thought Leader Award in support of his research into metabolic reprogramming in the earliest stages of cancer. He is internationally recognized for basic and translational research in cancer, aging and age-associated degenerative disorders. He is only the fourth full-time president in the 70-year history of MD Anderson. (press release)

Dr. Robert E. Gerszten

Robert Gerszten, M.D.
Massachusetts General Hospital
Institute for Heart, Vascular and Stroke Care.
Director of Clinical and Translational Research
Awarded: November 2012

Dr. Robert E. Gerszten received an Agilent Thought Leader award in support of his research on the discovery of metabolite biomarkers for cardiovascular and related metabolic diseases. Dr Gerszten has pioneered the use of proteomics and metabolomics approaches to identify biomarkers of these diseases using the Framingham heart study cohort. (press release)

Dr. Jens Frisvad

Dr. Jens Frisvad
Technical University of Denmark
Department of Systems Biology
Center for Microbial Biotechnology
Lyngby, Denmark
Professor
Awarded: May 2012

Prof. Frisvad's research is primarily in the area of fungi. His work focuses on the biochemical diversity in molds with a view to finding new enzymes and secondary metabolites which can be used in new drugs. In addition, he works on projects involving the study of mycotoxins and molds from Penicillium and Aspergillus, in an effort to prevent toxin-formation in food, indoor climates, and biotechnological products. (press release)

Dr. Russell Thomas

Dr. Russell Thomas
Hamner Institutes for Health Sciences
Director, Institute for Chemical Safety Sciences
Director, Center for Genomic Biology and Bioinformatics
Senior Investigator
Awarded: December 2011

Russell S. Thomas, Ph.D., of the Hamner Institutes for Health Sciences has been selected for an Agilent Thought Leader Award to support his work developing methods to predict drug-induced liver injury. The award includes funding from the Agilent Technologies Foundation as well as instrumentation from the company, including a 6460 triple quadrupole LC/MS and an Agilent microarray scanner. Dr. Thomas is director of the Institute for Chemical Safety Sciences at the Hamner, where researchers are applying a systems biology approach in an effort to predict drug-induced liver injury. (press release)

Dr. Chris Evelo

Dr. Chris Evelo
Maastricht University
Department Head, Bioinformatics BiGCaT
Awarded: November 2011

Dr. Chris Evelo at the department of bioinformatics at Maastricht University is the recipient of an Agilent Thought Leader Award supporting development of software to integrate different types of biological data. The goal of this award is to help accelerate breakthroughs in disease research by facilitating integrative systems biology approaches. The Evelo Lab helped develop WikiPathways.org as a community-curated platform for structuring multi-omics data and the associated open-access pathway analysis tool PathVisio. (press release)

Dr. Steven Carr

Dr. Steven Carr
Broad Institute
Senior Scientific Leader, Protein Biochemistry and Proteomics
Awarded: October 2011

Dr. Steven Carr of the Broad Institute (affiliated with the Massachusetts Institute of Technology and Harvard University) has been selected for an Agilent Thought Leader Award. The award will support Carrs efforts to develop new technologies for analyzing proteins and peptides, intended to help doctors diagnose illnesses such as cardiovascular disease, breast cancer and ovarian cancer. (press release)

Prof. Gerhard Wagner

Dr. Gerhard Wagner
Harvard Medical School
Department of Biological Chemistry and Molecular Pharmacology
Awarded: August 2011

Dr. Gerhard Wagner of the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School received an Agilent Thought Leader award in support of his effort to develop methods for studying biologically relevant systems that pose a serious challenge for modern structural biology tools. Prof. Wagner's work will greatly enhance the impact of NMR spectroscopy for large protein assignment and structure determination by matching the capabilities of modern high-field instruments with suitable acquisition and processing methods. (press release)

Dr. Adam Arkin
Dr. Adam Arkin
University of California, Berkeley
Director, Synthetic Biology Institute
Dean A. Richard Newton Memorial Professor,
Department of Bioengineering
Director, Physical Biosciences Division, Lawrence Berkeley National Lab
Awarded: April 2011

Adam Arkin, director of SBI and of the Physical Biosciences Division at LBNL, is the Dean A. Richard Newton Memorial Professor in UC Berkeleys Department of Bioengineering. He is also co-director of the Virtual Institute of Microbial Stress and Survival, director of bioinformatics at the Joint Bioenergy Institute, and co-director of BIOFAB (International Open Facility Advancing Biotechnology). His research centers on uncovering the evolutionary design principles of cellular networks and populations and exploiting them for applications. He and colleagues are developing a framework to facilitate applications in health, the environment, and bioenergy by combining comparative functional genomics, quantitative measurement of cellular dynamics, biophysical modeling of cellular networks, and cellular circuit design. (press release)

Dr. Bart Weimer
Dr. Bart Weimer
School of Veterinary Medicine
University of California, Davis
Professor, Population Health & Reproduction
Awarded: January 2011

Dr. Weimer's laboratory group at the School of Veterinary Medicine focuses on microbial physiology and function. Research on host/microbe interactions has led to the elucidation of the competitive binding of beneficial bacteria to the gut epithelium and the resulting displacement of pathogenic bacteria such as salmonella. Using genomics and functional genomics gene expression, metabolomics, proteomics, and metagenomics Dr. Weimer's program examines the mechanisms of gene interplay to produce a specific phenotype and the metabolism involved in the process.

Dr. David Botstein
Dr. David Botstein
Princeton University
Lewis-Sigler Institute for Integrative Genomics
Awarded: November 2010

Dr. David Botstein, professor and director of the Lewis-Sigler Institute for Integrative Genomics and the Center for Quantitative Biology at Princeton University, received an Agilent Thought Leader award in support of his research in the area of genomics. This award of cash funding and Agilent products to the Lewis-Sigler Institute for Integrative Genomics will allow Dr. Botstein to produce the most complete genomic, proteomic and metabolomic data sets from any eukaryote (organism with cells containing membrane-enclosed structures including nucleus) to date. (press release)

Dr. Hailu Kinde
Dr. Hailu Kinde, DVM, MPVM
UC Davis School of Veterinary Medicine California Animal Health and Food Safety Laboratory
Awarded: October 2010

Dr. Hailu Kinde, professor at the California Animal Health and Food Safety Laboratory System, received an Agilent Thought Leader award in support of his research in the area of food safety. This award of cash funding and Agilent products to the UC Davis School of Veterinary Medicine will allow Dr. Kinde to focus on the development of a new process that can reduce the time required to identify food-borne pathogens from several days to only a few hours. (press release)

Dr. Thomas Hartung
Dr. Thomas Hartung
Director for the Center for Alternatives to Animal Testing (CAAT)
Johns Hopkins University
Bloomberg School of Public Health
Awarded: August 2010

Dr. Thomas Hartung received an Agilent Thought Leader award in support of his research on for the use of toxicity pathways to predict developmental neurotoxicity. Through this award of funding from the Agilent Foundation and a company donation of instruments to the Center for Alternatives to Animal Testing (CAAT) at the Johns Hopkins Bloomberg School of Public Health, Dr. Hartung will focus his research on the identification of novel toxicity pathways by combining two promising cell culture models with emerging metabolomics. This work could help identify possible contributions of chemicals to disorders such as autism and attention hyperactivity disorders. (press release)

Dr. James J. Collins
Dr. James Collins
Professor of Biomedical Engineering
Wyss Institute for Biologically Inspired Engineering
Awarded: July 2010

Dr. James Collins is developing innovative ways to reprogram organisms, particularly bacteria, to perform desired tasks, such as attacking tumors and guiding development of stem cells. These programmed bacteria could lead to cheaper drugs, greener fuels, and more effective treatments for antibiotic-resistant infections and diseases. He is a pioneer in systems biology, stochastic resonance, biological dynamics, and neurostimulation, with the goal of improving the function of physiological and biological systems. (press release)

Dr. George Church
Dr. George Church
Professor of Genetics
Harvard Medical School
Director of the Center for Computational Genetics
Wyss Institute for Biologically Inspired Engineering
Awarded: July 2010

Dr. George Church is Professor of Genetics at Harvard Medical School and Director of NIH-CEGS and DOE-GTL Genomics Centers. He has pioneered technology innovations early in the development of key fields in chemistry and biomedicine with 10 US Patents granted and several pending. As part of technology transfer to the commercial sector he has served on 22 scientific advisory boards. In 1976, his crystallographic software lead to the first high-resolution folded-RNA structure (a decade before similar structures important for ribozymes, aptamers, and RNAi). (press release)

Dr. Don Ingber

Dr. Don Ingber
Wyss Institute Founding Director
and Core Faculty Member
Platform Leader, Biomimetic Microsystems
Awarded: July 2010

Dr. Ingber is Founding Director of the Wyss Institute and a leader in the emerging field of biologically inspired engineering. He oversees a multifaceted effort to identify the mechanisms that living organisms use to self assemble and to apply these design principles to develop advanced materials and devices. Dr. Ingber was the first researcher to recognize that tensegrity architecture (in which a system stabilizes itself mechanically by balancing local compression with continuous tension) is a fundamental principle in the way living organisms are structured at the nanometer scale. (press release)

Dr. Janne Lehti

Dr. Janne Lehtio
Karolinska Institute
Department of Oncology-Pathology
Science for Life Laboratory
Awarded: June 2010

Dr. Janne Lehtio has worked on clinical proteomics both in academia and biotech industry. In 2004, Dr. Lehtio was selected to build mass spectrometry based proteomics at Karolinska University Hospital and continues his proteomics research there. Today, Dr. Lehtio leads a mass-spectrometry-based proteomics group at Karolinska Institutet focusing on quantitative proteomics methods development and cancer proteomics. In recent year his lab has developed several methods for clinical proteomics and currently uses these methods to understand proteome changes related to cancer therapy.

Dr. Pauline Rudd

Dr. Pauline Rudd
Professor of Glycobiology
University College Dublin
National Institute for Bioprocessing Research and Training (NIBRT)
Awarded: May 2010

Dr. Pauline Rudd received an Agilent Thought Leader award in March 2010 in support of emerging glycomics research through a grant of funding and instruments to the National Institute for Bioprocessing Research and Training (NIBRT) at the University College Dublin in Ireland. The goal of the research is to develop novel approaches to analyze protein glycosylation as part of the characterization process of recombinant protein drugs and to study disease glycan biomarkers using liquid chromatography mass spectrometry. (press release)