MassHunter BioConfirm for Your Lab
BioConfirm Software
Agilent MassHunter BioConfirm software offers comprehensive workflows for biomolecule characterization, including oligonucleotide and intact protein analysis, peptide mapping, and released glycan profiling. It is part of a comprehensive MS solution for LC/TOF and LC/Q-TOF analysis of biopharmaceutical products such as monoclonal antibodies. Available with advanced security features and built-in technical controls, it helps to minimize risk and preserve data integrity.
From automated sample preparation to separation, detection, analysis, and reporting, Agilent biopharma workflows give any user access to advanced LC/MS capabilities—with tools like drug-to-antibody ratio (DAR) calculator, report templates, and Agilent MassHunter WalkUp integration.
From automated sample preparation to separation, detection, analysis, and reporting, Agilent biopharma workflows give any user access to advanced LC/MS capabilities—with tools like drug-to-antibody ratio (DAR) calculator, report templates, and Agilent MassHunter WalkUp integration.
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Product Details
Features
- MassHunter BioConfirm software is part of the end-to-end solutions offered by Agilent for biopharma workflows, also including the Agilent AssayMAP Bravo protein sample prep platform, Agilent 1290 Infinity III bio LC, and Agilent LC/TOF and LC/Q-TOF systems, consumables, and services
- MassHunter WalkUp provides sample submitters access to expert LC/MS capabilities without requiring them to be experts in liquid chromatography/mass spectrometry
- Compatible with Agilent MassHunter Acquisition for LC/MS (all models) or Agilent OpenLab CDS 3.0 software (6230C, 6545XT, Revident)
- Compliance-ready features keep you in control - with e-signatures, advanced security capabilities, and built-in technical controls, BioConfirm software can minimize security risks while helping to preserve data integrity
- Sequence manager and Chemical Data Dictionary are now client/server capable
- For the characterization of oligonucleotides, enables quick setup of impurity analysis and sequence confirmation workflows using your preferred definitions for building blocks, linkers, and modifications
- For intact protein analysis, rapidly deconvolutes your intact protein data to determine molecular weights and confirm post-translational modifications (PTMs)
- For peptide mapping, performs sequence confirmation with confidence and review multiple samples (for example, different digest enzymes) at the same time using our Sequence Coverage Map
- The released glycans workflow relies on a curated database for glycans for easy setup of the analysis, and accommodates many commercial and custom tags
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Technology
Frequently Asked Questions - MassHunter BioConfirm Software
MassHunter BioConfirm software enables workflows for routine characterization of oligonucleotides, protein digests, intact proteins, and released glycans within a single program in a compliance-ready environment. Learn more about these workflows and frequently asked questions.
Learn MoreApplications
Literature
- Key Literature
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Agilent MassHunter BioConfirm Software Brochure
BioConfirm Software- Rapid Characterization of Protein Biopharmaceuticals.
- Brochures
- English
- 19 May 2022
- 1.41 MB
Ensuring Regulatory Compliance and Data Integrity with MassHunter Software Solutions
A technical overview of the compliance features for LC/TOF and LC/Q-TOF.
- Technical Overviews
- English
- 15 Oct 2021
- 1.34 MB
- Application Notes
- Brochures
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- Posters
- Technical Overviews
- White Papers
Support
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Agilent LC/MS and GC/MS MassHunter Software Support Lifecycle Policy
This page describes the support lifecycle policy and status of the LC/MS and GC/MS MassHunter software products produced by Agilent.
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Customer Testimonials
Dimas Echeverria
Director, Nucleic Acid Chemistry Center, UMass Chan Medical School
“BioConfirm has been a game-changer. It helps us to automate impurity profiling across different oligo types, saving time and improving consistency.”
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Training & Events
Meet regulatory compliance for biopharma with new mass spec software solutions
Data integrity plays a key role in ensuring the quality and safety of biopharmaceutical products. In this webinar, explore the current regulatory landscape and how new mass spectrometry software updates can enable you to address data integrity and meet regulatory requirements, such as US FDA 21 CFR Part 11 and EU Annex 11. Learn how advanced security features and built-in technical controls minimize security risks when applied to workflows for the analysis of intact proteins, protein digests and released glycans, by enabling setup of user roles, user permissions, audit trails, checksums, and secure content management across all software modules.
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